Results 51 to 60 of about 1,610,795 (266)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

B and T cell responses to pre-erythrocytic R21/Matrix-M and blood-stage RH5.1/Matrix-M malaria vaccines in endemic settings

Frontiers in Immunology
IntroductionThere is great interest in combining the licensed pre-erythrocytic malaria vaccine R21/Matrix-M® and the blood-stage candidate vaccine RH5.1/Matrix-M® to maximise efficacy against Plasmodium falciparum malaria.
Caroline K. Bundi, Caroline K. Bundi, Olivia Muñoz, Elizabeth Kibwana, Duncan Bellamy, Lisa Stockdale, Jordan R. Barrett, Jordan R. Barrett, Kirsty McHugh, Kirsty McHugh, Ivanny Mtaka, Wilmina Kalinga, Domtila Kimani, Lydia Nyamako, Kelvias Keter, Rodney Ogwang, Adrian V. S. Hill, Philip Bejon, Philip Bejon, Mainga Hamaluba, Mainga Hamaluba, Sarah E. Silk, Sarah E. Silk, Angela M. Minassian, Angela M. Minassian, Simon J. Draper, Simon J. Draper, Ally I. Olotu, Melissa C. Kapulu, Melissa C. Kapulu, Katie J. Ewer, Carolyn M. Nielsen, Carolyn M. Nielsen   +32 more
doaj   +1 more source

Generalized AOR Algorithms for Linear Complementarity Problem

Journal of Algorithms & Computational Technology, 2007
In this paper, we propose a class of generalized accelerated overrelaxation (GAOR) methods, in which one special case reduces to the generalized successive overrelaxation(GSOR) methods, for solving a linear complementarity problem LCP ( M, q ...
Dongjin Yuan, Hui Zhang
doaj   +1 more source

The M-theory S-matrix from ABJM: beyond 11D supergravity

Journal of High Energy Physics, 2018
We show that by studying the flat spacetime limit of the Mellin amplitude associated with the four-point correlation function of scalar operators in the stress tensor multiplet of ABJM theory, one can produce the momentum expansion of the M-theory four ...
Shai M. Chester, Silviu S. Pufu, Xi Yin
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context

BMJ Global Health
Background The R21/Matrix-M malaria vaccine has been shown to provide high protective efficacy against malaria in a phase III trial, and has been recommended for use by WHO. The vaccine will soon be deployed at scale in sub-Saharan Africa.
Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko   +13 more
doaj   +1 more source

Positive eigenvector of nonlinear eigenvalue problem with a singular M-matrix and Newton-SOR iterative solution

Journal of Inequalities and Applications, 2016
Some sufficient conditions are proposed in this paper such that the nonlinear eigenvalue problem with an irreducible singular M-matrix has a unique positive eigenvector.
Cheng-yi Zhang, Yao-yan Song, Shuanghua Luo   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Exact lattice bosonization of finite N matrix quantum mechanics and c = 1

Journal of High Energy Physics
We describe a new exact lattice bosonization of matrix quantum mechanics (equivalently of non-relativistic fermions) that is valid for arbitrary rank N of the matrix.
Gautam Mandal, Ajay Mohan
doaj   +1 more source

Matrix Pencil Optimal Iterative Algorithms and Restarted Versions for Linear Matrix Equation and Pseudoinverse

Mathematics
We derive a double-optimal iterative algorithm (DOIA) in an m-degree matrix pencil Krylov subspace to solve a rectangular linear matrix equation. Expressing the iterative solution in a matrix pencil and using two optimization techniques, we determine the
Chein-Shan Liu, Chung-Lun Kuo, Chih-Wen Chang   +2 more
doaj   +1 more source