Results 51 to 60 of about 27,057,635 (304)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Improving TiB2 dispersion in Al-Si composites by interfacial projection: High-throughput first-principles calculations and experimental verification

open access: yesMaterials & Design
The dispersion of reinforced particles is crucial in improving the mechanical properties of ceramic particles reinforced Al matrix composites. In this work, a novel interfacial projection strategy was proposed to improve the dispersion of TiB2 particles ...
Hongyi Zhu   +9 more
doaj   +1 more source

M-matrix generalized inverses of M-matrices

open access: yesLinear Algebra and its Applications, 1997
The condition when the group inverse of the associated singular irreducible \(M\)-matrix corresponding to a nonnegative, irreducible and stochastic matrix will be an \(M\)-matrix is that this matrix lies in a small wedge about a rank one nonnegative matrix.
Chen, Yonghong, Neumann, M.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Target space entanglement in Matrix Models

open access: yesJournal of High Energy Physics, 2021
We study target space entanglement in gauged multi-matrix models as models of entanglement between groups of D-branes separated by a planar entangling surface, paying close attention to the implementation of gauge invariance.
Harsha R. Hampapura   +2 more
doaj   +1 more source

The symmetric inverse M-matrix completion problem

open access: yesLinear Algebra and its Applications, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Johnson, Charles R., Smith, Ronald L.
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The M-theory S-matrix from ABJM: beyond 11D supergravity

open access: yesJournal of High Energy Physics, 2018
We show that by studying the flat spacetime limit of the Mellin amplitude associated with the four-point correlation function of scalar operators in the stress tensor multiplet of ABJM theory, one can produce the momentum expansion of the M-theory four ...
Shai M. Chester, Silviu S. Pufu, Xi Yin
doaj   +1 more source

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