Results 71 to 80 of about 1,610,795 (266)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs
Veterinary Research, 2017 Saponin-based adjuvants have been widely used to enhance humoral and cellular immune responses in many species, but their mode of action is not fully understood.
Viktor Ahlberg +5 more
doaj +1 more source
Precipitation of M23C6 Secondary Carbide Particles in Fe-Cr-Mn-C Alloy during Heat Treatment Process
Metals, 2020 The initial as-cast microstructure of high-chromium white cast iron (2.08% C, 12.1% Cr), including austenitic dendrites in a matrix of a eutectic mixture of austenite and M7C3 carbides.
Nguyen Thi Hoang Oanh +1 more
doaj +1 more source
Linear Algebra and its Applications, 1977 AbstractOne aspect of the inverse M-matrix problem can be posed as follows. Given a positive n × n matrix A=(aij) which has been scaled to have unit diagonal elements and off-diagonal elements which satisfy 0 < y ⩽ aij ⩽ x < 1, what additional element conditions will guarantee that the inverse of A exists and is an M-matrix?
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Finite Orthogonal M Matrix Polynomials
SymmetryIn this study, we aim to construct a finite set of orthogonal matrix polynomials for the first time, along with their finite orthogonality, matrix differential equation, Rodrigues’ formula, several recurrence relations including three-term relation, forward and backward shift operators, generating functions, integral representation and their relation ...
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Sign determinacy of M-matrix minors
Linear Algebra and its Applications, 1987 Let A be a (singular or non-singular) M-matrix, and let G(A) denote its undirected graph. The main result is that if the longest simple cycle of G(A) has length not exceeding 3 then the sign of any minor of A depends only on G(A) and not on the magnitude of the entries of A.
Johnson, Charles R. +3 more
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source