Results 61 to 70 of about 1,610,795 (266)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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npj VaccinesMatrix-M® adjuvant, containing saponins, delivers a potent adjuvant effect and good safety profile. Given that Matrix-M is composed of Matrix-A and Matrix-C particles, comprising different saponin fractions, understanding their distinct roles can provide
Behdad Zarnegar +17 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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Fuzzy Symmetric Solutions of Fuzzy Matrix Equations
Advances in Fuzzy Systems, 2012 The fuzzy symmetric solution of fuzzy matrix equation AX˜=B˜, in which A is a crisp m×m nonsingular matrix and B˜ is an m×n fuzzy numbers matrix with nonzero spreads, is investigated.
Xiaobin Guo, Dequan Shang
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The Matrix-M™ adjuvant: A critical component of vaccines for the 21st century
Human Vaccines & Immunotherapeutics, 2023 Matrix-M™ adjuvant is a key component of several novel vaccine candidates. The Matrix-M adjuvant consists of two distinct fractions of saponins purified from the Quillaja saponaria Molina tree, combined with cholesterol and phospholipids to form 40-nm ...
Linda Stertman +11 more
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On regular splittings of an M-matrix
Linear Algebra and its Applications, 1989 Some results on regular splittings of M-matrices are proved. The study is motivated by a recent work of \textit{H. Schneider} [ibid. 58, 407-424 (1984; Zbl 0561.65020)]. It is shown, first, that if A is a nonsingular M-matrix and \(A=M-N\) is a regular splitting then this splitting is a graph compatible one, and if A is just an M-matrix but \(A=M-N ...
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A stable test to check if a matrix is a nonsingular $M$-matrix [PDF]
Mathematics of Computation, 2004 A real matrix with non-positive off-diagonal elements is called a \(Z\)-matrix. Non-singular \(M\)-matrices form a subclass of \(Z\)-matrices. In this paper, a test to check the non-singularity of an \(M\)-matrix is presented such that the related growth factor is bounded above by \(n-1\). In the worst case, the proposed test adds \(O(n^2)\) elementary
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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On Markham's M-matrix properties
Linear Algebra and its Applications, 1987 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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