Results 131 to 140 of about 28,693,335 (281)

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

open access: yesAdvanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin   +7 more
wiley   +1 more source

HDAC inhibition blocks Glyc-alb induced reduction in TEER.

open access: yes, 2016
Administration of 100 μg/mL Glyc-alb with and without TSA pretreatment (1 h) to (A) ARPE 19 cells and (B) hfRPE cells showing the resulting TEER at 6 h post treatment compared to the administration of the same concentration of Alb.
Danielle Desjardins (735474)   +3 more
core   +1 more source

High‐Current‐Density Acidic CO2 Electroreduction to Formic Acid Enabled by Multiscale Microenvironment Regulation Over Defect‐Rich Sn/SnOx

open access: yesAdvanced Science, EarlyView.
Acidic CO2 electroreduction to formic acid is enabled by integrating mixed Sn/SnOx nanoclusters, K+‐regulated interfacial solvation, and Janus wettability. Coordinated control of active sites, interfacial water, and gas‐liquid transport suppresses hydrogen evolution and delivers approximately 85% HCOOH Faradaic efficiency at 400 mA cm−2.
Qiaoqi Guo   +8 more
wiley   +1 more source

Clinical Outcomes of Inpatient Mitral Transcatheter Edge-To-Edge Repair in Patients Hospitalized with Decompensated Heart Failure

open access: yesCJC Open
Background: Mitral transcatheter edge-to-edge repair (M-TEER) is an established therapy for patients with severe mitral regurgitation (MR), with randomized trials demonstrating improved outcomes in selected ambulatory populations.
Loai Almazroa, MD   +17 more
doaj   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Association Between Preoperative Gait Speed and Mortality in Patients with Transcatheter Edge-to-Edge Mitral Repair

open access: yesDiseases
Background: Transcatheter Edge-to-Edge Repair (TEER) is a therapeutic option established for older patients with heart failure and concomitant mitral regurgitation. Frailty is associated with prognosis after transcatheter valve interventions.
Hirotaka Fukuda   +6 more
doaj   +1 more source

Trans-epithelial electric resistance (TEER) in the presence of compounds increasing Lucifer yellow (LY)-transport.

open access: yes, 2013
TEER was measured at the end of the experiment. Deviation (dev) is calculated as the absolute value of the difference between the two experiments divided by 2.
Knut G. Berdal (281269)   +5 more
core   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

open access: yesAdvanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang   +5 more
wiley   +1 more source

IL-18 decreases TEER in Caco2 monolayers.

open access: yes, 2018
The TEER was measured during 24 hours after addition of 10 ng/ml of IL-18, 10 ng/ml IL-1β or 100 ng/ml Tat to the cell monolayers. Note dramatic decrease of the TEER occurring at hour 6 post-exposure by both IL-18 and Tat.
Vikram Mehraj (376026)   +7 more
core   +1 more source

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