Results 31 to 40 of about 22,774,664 (248)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Clinical Impact of Early Changes in Serum Albumin on Patient Prognosis After Mitral‐Transcatheter Edge‐to‐Edge Repair

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Low serum albumin levels indicate frailty and are strong predictors of poor prognosis after mitral transcatheter edge‐to‐edge repair (M‐TEER); however, albumin levels are expected to improve in response to treatment for mitral regurgitation ...
Kenichi Shibata, Masanori Yamamoto, Ai Kagase, Takahiro Tokuda, Hiroshi Tsunamoto, Tetsuro Shimura, Azusa Kurita, Ryo Yamaguchi, Mike Saji, Yuki Izumi, Masahiko Asami, Yusuke Enta, Shinichi Shirai, Masaki Izumo, Shingo Mizuno, Yusuke Watanabe, Makoto Amaki, Kazuhisa Kodama, Junichi Yamaguchi, Toru Naganuma, Hiroki Bota, Yohei Ohno, Masahiro Yamawaki, Daisuke Hachinohe, Hiroshi Ueno, Gaku Nakazawa, Toshiaki Otsuka, Shunsuke Kubo, Kentaro Hayashida   +28 more
doaj   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Change in Dicrotic Notch Index Predicts Outcomes in Patients Undergoing Transcatheter Edge-to-Edge Repair for Mitral Regurgitation

Structural Heart
Background: Changes in the dicrotic notch characteristics in the aortic pressure waveform have not been adequately studied with mitral transcatheter edge-to-edge repair (M-TEER).
Vishwum Kapadia, Shivabalan Kathavarayan Ramu, MD, Maryam Majeed-Saidan, MD, Rhonda Miyasaka, MD, Serge Harb, MD, Amar Krishnaswamy, MD   +5 more
doaj   +1 more source

Symmetry‐Guided Multifunctional Acoustic System Based on Mechanically Actuated Sonic Crystals

Advanced Engineering Materials, EarlyView.
This study presents the design, simulation, and experimental validation of amultifunctional acoustic metamaterial based on rotationally engineered sonic crystals.By tuning cylinder orientations, controllable band gaps and six distinct functionalities—including switching, topological insulation, beam splitting, and logic operations—areachieved ...
Yuanyan Zhao, Sriram Subramanian, Gianluca Memoli   +2 more
wiley   +1 more source

To clip or not to clip? A review of precise risk assessment in the contemporary era of transcatheter edge-to-edge mitral and tricuspid valve repair

Frontiers in Cardiovascular Medicine
Transcatheter edge-to-edge mitral and tricuspid valve repair (M-TEER, T-TEER) have emerged as meaningful treatment modalities among patients at high surgical risk suffering from valvular heart disease.
Felix Ausbuettel, Carlo-Federico Fichera
doaj   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Outcomes of Transcatheter Edge‐to‐Edge Repair in Potentially Favorable Candidates for Left Ventricular Assist Device: Evidence From the OCEAN‐Mitral Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Transcatheter edge‐to‐edge repair of the mitral valve (M‐TEER) has shown promising outcomes in patients with advanced heart failure and significant mitral regurgitation.
Shuhei Tanaka, Teruhiko Imamura, Yuki Hida, Ryuichi Ushijima, Nobuyuki Fukuda, Hiroshi Ueno, Koichiro Kinugawa, Masanori Yamamoto, Shunsuke Kubo, Yuki Izumi, Mike Saji, Masahiko Asami, Yusuke Enta, Shinichi Shirai, Masaki Izumo, Shingo Mizuno, Yusuke Watanabe, Makoto Amaki, Kazuhisa Kodama, Hisao Otsuki, Toru Naganuma, Hiroki Bota, Yohei Ohno, Masahiro Yamawaki, Gaku Nakazawa, Daisuke Hachinohe, Atsushi Sugiura, Tetsuro Shimura, Toshiaki Otsuka, Kentaro Hayashida   +29 more
doaj   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Changes in transepithelial electrical resistance (TEER) of additional enteroid monolayers following infection with wildtype or CF-deficient strains.

, 2022
TEER values of differentiated ileal enteroid monolayers (46I) were recorded prior to infection and after 4 hr incubation. The change in TEER is expressed as TEER percentage change. Data presented are from four independent experiments. Each dot represents
Emily M. Smith (1326564), Eileen M. Barry (8663025), Christen L. Grassel (13155228), Antonia Papadimas (13155231), Jennifer Foulke-Abel (434893)   +4 more
core   +1 more source