Results 51 to 60 of about 22,774,664 (248)

Measurement of Transepithelial Electrical Resistance (TEER).

, 2014
A - TEER of unstimulated PNECs and PBECs cultured for 28 d. Values are expressed as mean ± SD. No significant difference was observed in the TEER values between the groups. B - TEER of PNECs and PBECs cultured with 20 ng/ml IL-13 for 28 d.
Jeremy C. Parker (411704), Michael D Shields (514966), Michael E. McBrien (514965), Liam G. Heaney (411708), Grzegorz Skibinski (411706), Surendran Thavagnanam (411705)   +5 more
core   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Design of a TEER monitoring setup for a Gut-on-Chip model

, 2023
LAUREA MAGISTRALELa via orale è la più utilizzata e la meno invasiva per la somministrazione di farmaci. Tuttavia, lo sviluppo di questi farmaci è spesso ostacolato dal processo di assorbimento che avviene attraverso l'epitelio intestinale.
D'Antonio, Micol
core  

Effect of TNFα on TEER at 24 h and effect of Dex and RU486, a glucocorticoid receptor antagonist, on TEER (not relative value) in alveolar epithelial cells (AECs).

, 2023
(A) TEER in AECs stimulated with ± 10 ng/mL recombinant rat TNFα for 24 h, n = 6 (six independent experiments). (B) TEER in AECs stimulated with ± 10 ng/mL recombinant rat TNFα for 48 h and ± 1,000 nM Dex for 24 h, n = 6 (six independent experiments). (C)
Koichiro Asano (3438395), Hiroto Takiguchi (3910063), Yoko Ito (179758), Naokata Kutsuzawa (9690187), Chinatsu Kohno (9690190), Shizuko Kagawa (12188510)   +5 more
core   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Mitral Transcatheter Edge-to-Edge Repair in Acute Ischemic Mitral Regurgitation: Current Evidence and Future Perspectives

Reviews in Cardiovascular Medicine
Acute ischemic mitral regurgitation is a rare but potentially catastrophic complication following acute myocardial infarction (AMI), characterized by severe clinical presentation and high mortality.
Marco Frazzetto, Claudio Sanfilippo, Francesco Briguglio, Chiara Giacalone, Claudia Contrafatto, Andrea Munafò, Michela Bonanni, Jacopo Oreglia, Giuliano Costa, Guilherme Attizzani, Davide Capodanno, Carmelo Grasso   +11 more
doaj   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Clinical Impact of Early Nutritional Reversibility After Mitral Valve Transcatheter Edge-to-Edge Repair

JACC: Advances
Background: Mitral valve transcatheter edge-to-edge repair (M-TEER) is an established effective treatment for patients with mitral regurgitation. The Geriatric Nutritional Risk Index (GNRI) is a well-known nutritional marker that predicts mortality risk;
Kenichi Shibata, PT, Masanori Yamamoto, MD, Ai Kagase, MD, Takahiro Tokuda, MD, Hiroshi Tsunamoto, MD, Atsushi Sugiura, MD, Tetsuro Shimura, MD, Azusa Kurita, MD, Ryo Yamaguchi, MD, Mike Saji, MD, Yuki Izumi, MD, Masahiko Asami, MD, Yusuke Enta, MD, Shinichi Shirai, MD, Masaki Izumo, MD, Shingo Mizuno, MD, Yusuke Watanabe, MD, Makoto Amaki, MD, Kazuhisa Kodama, MD, Hisao Otsuki, MD, Toru Naganuma, MD, Hiroki Bota, MD, Yohei Ohno, MD, Masahiro Yamawaki, MD, Daisuke Hachinohe, MD, Hiroshi Ueno, MD, Gaku Nakazawa, MD, Toshiaki Otsuka, MD, Shunsuke Kubo, MD, Kentaro Hayashida, MD   +29 more
doaj   +1 more source

IL-18 decreases TEER in Caco2 monolayers.

, 2018
The TEER was measured during 24 hours after addition of 10 ng/ml of IL-18, 10 ng/ml IL-1β or 100 ng/ml Tat to the cell monolayers. Note dramatic decrease of the TEER occurring at hour 6 post-exposure by both IL-18 and Tat.
Vikram Mehraj (376026), Ossama Allam (5043434), Devendra Amre (356664), Mohammad-Ali Jenabian (49586), Jean-Pierre Routy (118465), Cecile Tremblay (5043428), Ali Ahmad (4805907), Suzanne Samarani (5043431)   +7 more
core   +1 more source