Results 141 to 150 of about 875,624 (353)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

COVARIANT FORMULATION OF M-THEORY [PDF]

open access: yesInternational Journal of Modern Physics A, 2009
We propose the bosonic part of an action that defines M-theory. It possesses manifest SO(1, 10) symmetry and constructed based on the Lorentzian 3-algebra associated with U(N) Lie algebra. From our action, we derive the bosonic sector of BFSS matrix theory and IIB matrix model in the naive large N limit by taking appropriate vacua.
openaire   +5 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

K-theory and phase transitions at high energies

open access: yesPracì Mìžnarodnogo Geometričnogo Centru, 2016
The duality between E8xE8 heteritic string on manifold K3xT2 and Type IIA string compactified on a Calabi-Yau manifold induces a correspondence between vector bundles on K3xT2 and Calabi-Yau manifolds.
T. V. Obikhod
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Contribution of M. Maknys to number theory

open access: yesLietuvos Matematikos Rinkinys, 2004
In the paper a survey of works in the number theory of M. Maknys is presented.
Antanas Laurinčikas
doaj   +1 more source

Aspects of Heterotic/M-Theory Duality in D=3 [PDF]

open access: yesarXiv, 1999
We study the duality between M-theory compactified on Calabi-Yau fourfolds and the heterotic string compactified on Calabi-Yau threefolds times a circle. Our analysis is based on a comparison of the low energy effective actions in three dimensions.
arxiv  

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Bosonic M-Theory From a Kac-Moody Algebra Perspective [PDF]

open access: yesarXiv
We study the existence of a bosonic m-theory extension of the 10D and 26D closed bosonic string in terms of Kac-Moody algebras. We argue that K11 and K27 are symmetries which protect the coefficients of the closed bosonic string in 10 and 26 dimensions.
arxiv  

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