Results 151 to 160 of about 21,308,721 (308)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Mirage cosmology in M-theory

open access: yesPhysics Letters B, 2002
We extend the idea of mirage cosmology to M-theory. Considering the motion of a probe brane in the M-theory background generated by a stack of non-threshold (M2,M5) bound states, we study the cosmological evolution of the brane universe in this background. We estimate the range of $r$ where the formalism is valid.
openaire   +2 more sources

Lorentz invariant field theory on κ-Minkowski space

open access: yes, 2010
It is by now well established that the momentum space associated with the non-commutative κ-Minkowski space is a submanifold of de Sitter space. It has been noted recently that field theories built on such momentum space suffer from a subtle form of ...
Sub String Theory Cosmology and ElemPart   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Half-maximal consistent truncations using EFT and the M-theory / heterotic duality

open access: yes, 2017
One of the most powerful applications of exceptional and double field theories has been in the study of consistent truncations via generalised Scherk-Schwarz reductions which preserve all supersymmetries.
Malek, Emanuel
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The QCD trace anomaly at strong coupling from M-theory. [PDF]

open access: yesEur Phys J C Part Fields, 2020
Misra A, Gale C.
europepmc   +1 more source

Four-dimensional black hole entropy from F-theory

open access: yes, 2019
We study the central charges and levels of a two-dimensional N = (0, 4) superconformal field theory describing four-dimensional BPS black holes in F-theory.
Kilian Mayer   +10 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

On the Theory of Zm Linear Codes: the Zm Linear Preparata and Goethals Codes for m>2

open access: yes
Let m ∈ N and Zm def/ ={0,1, ⋯, m-1} be the m ary alphabet. A Zm linear code of length n ∈ N is a submodule of the module (Zmn,+mod m, Zm, · bmod m). This paper presents a significant lower bound for the minimum Lee distance dLee (C), of any Zm linear ...
Tallini, Luca G., Bose, Bella
core   +1 more source

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