Results 151 to 160 of about 946,279 (310)

String/M theory

open access: yes, 2000
This is a brief review of the present status, of some recent developments and of the open challenges in string/M theory.
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Twisted Fibrations in M/F-theory

open access: yesJournal of High Energy Physics
In this work we investigate 5-dimensional theories obtained from M-theory on genus one fibered threefolds which exhibit twisted algebras in their fibers.
Lara B. Anderson   +2 more
doaj   +1 more source

M-Theory

open access: yes, 2001
Comment: 11 pages LaTex file. No figures. Minor typos corrected.
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

M-Theory from Its Superalgebra [PDF]

open access: yes, 1999
These lectures explore what can be learnt about M-theory from its superalgebra. The first three lectures introduce the 'basic' branes of M-theory, and type II superstring theories, and show how the duality relations between them are encoded in the respective spacetime superalgebras.
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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