Results 81 to 90 of about 964,507 (280)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Macroscopic approaches to rotating neutron stars [PDF]
The macroscopic model for a neutron star (NS) as a perfect liquid drop at equilibrium is extended to rotating systems with a small frequency ω within the effective-surface (ES) approach.
A. A. Uleiev +8 more
doaj +1 more source
Multi-parametric and analytic families of four-dimensional AdS3 × ℝ (Janus) and AdS3 × ℝ+ (Hades) solutions are constructed in the SO(8) gauged supergravity that arises from the consistent reduction of eleven-dimensional supergravity on S7 .
Andrés Anabalón +2 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Singletons, doubletons and M-theory [PDF]
We identify the two dimensional AdS subsupergroup $OSp(16/2,R)$ of the M-theory supergroup $OSp(1/32,R)$ which captures the dynamics of $n$ $D0$-branes in the large $n$ limit of Matrix theory. The $Sp(2,R)$ factor in the even subgroup $SO(16) \times Sp(2,R)$ of $OSp(16/2,R)$ corresponds to the AdS extension of the Poincare symmetry of the longitudinal ...
Günaydin, M., Minic, D.
openaire +2 more sources
M-Theory Moduli Space and Cosmology [PDF]
We conduct a systematic search for a viable string/M-theory cosmology, focusing on cosmologies that include an era of slow-roll inflation, after which the moduli are stabilized and the Universe is in a state with an acceptably small cosmological constant.
A. Sen +42 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
COVARIANT FORMULATION OF M-THEORY [PDF]
We propose the bosonic part of an action that defines M-theory. It possesses manifest SO(1, 10) symmetry and constructed based on the Lorentzian 3-algebra associated with U(N) Lie algebra. From our action, we derive the bosonic sector of BFSS matrix theory and IIB matrix model in the naive large N limit by taking appropriate vacua.
openaire +2 more sources
Elliptic models and M-theory [PDF]
We give a unified analysis of four-dimensional elliptic models with N=2 supersymmetry and a simple gauge group, and their relation to M-theory. Explicit calculations of the Seiberg-Witten curves and the resulting one-instanton prepotential are presented.
Abolhasani +80 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

