Results 181 to 190 of about 449,265 (199)

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Lactobacillus‐Loaded Bioadhesive Hydrogel with Prolonged Retention and Microenvironmental Remodeling for Endometrial Repair and Fertility Restoration

Advanced Science, EarlyView.
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen, Hui Zhou, Yifei Li, Yi Liang, Yifan Zhang, Huiyu Huang, Qiuxian Xie, Youchen Tang, Huixia Ye, Yu Zhang   +9 more
wiley   +1 more source

Decreased expression of immune activator WARS1 and other pro-inflammatory mediators in type 1-like macrophages as an associated mode of action in response to fucoidan from marine brown algae. [PDF]

Front Immunol
Ostermann J, Gemoll T, Schnüttgen T, Tischhöfer MT, Plötze-Martin K, Fleckner J, Bruchhage KL, Alban S, Pries R.   +8 more
europepmc   +1 more source

Influence of side-hole configuration on recirculation in dual-lumen cannulas for veno-venous extracorporeal membrane oxygenation: a parametric computational fluid dynamics study. [PDF]

Front Bioeng Biotechnol
Zhu C, Ye P, Chang Z.
europepmc   +1 more source

Cortical-to-pallidal beta cascade underlies network pathophysiology in Parkinson's disease. [PDF]

Cell Rep Med
Choi JW, Alijanpourotaghsara A, Mirpour K, Chilukuri S, Pouratian N.   +4 more
europepmc   +1 more source

Mitochondrial reprogramming of alveolar macrophages by umbilical cord mesenchymal stem cells restores immune homeostasis in <i>Porphyromonas gingivalis</i> lipopolysaccharide-induced aspiration pneumonia. [PDF]

Mater Today Bio
Lin YF, Jhuang HY, Tsai MH, Wang HH, Liu KJ, Yen BL, Chen YW, Liu F, Wang LT.   +8 more
europepmc   +1 more source

A B1 SINE element within the mouse <i>Malat1</i> long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation. [PDF]

Sci Adv
Xiao W, Hann T, Perry Z, Pandey V, Cheng J, Wohlschlegel J, Pyle AM, Black DL.   +7 more
europepmc   +1 more source