Results 191 to 200 of about 95,825 (311)

D1.4 Monitoring and Evaluation Framework version M12

open access: yes
This deliverable introduces the Monitoring and EvaluaƟon (M&E) Framework for the ECHO project, encapsulaƟng the systemaƟc methodologies adopted to assess the effecƟveness and impact of the project's diverse acƟviƟes. At its core, the framework is designed to ensure that every component of the project aligns with the strategic objecƟves laid out in the ...
openaire   +1 more source

Clinical Significance of Drug–Drug Interaction Studies During Therapeutic Peptide Drug Development: Follow‐Up Investigation of Therapeutic Peptides Approved Between 2021 and 2024

open access: yesClinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT The risk of clinically relevant drug–drug interactions (DDIs) for therapeutic peptides remains unclear, mandating a comprehensive analysis for this modality. In our prior study, we analyzed DDIs for 31 peptide drugs approved between January 2008 and August 2021.
Carolina Säll   +6 more
wiley   +1 more source

Drug Interaction PBPK Modeling: Review of the Literature Exposes the Need for Increased Verification of Model Inputs and Outputs as Part of Credibility Assessment

open access: yesClinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT In vitro data are routinely used to support both static and physiologically based pharmacokinetic (PBPK) model‐based drug–drug interaction (DDI) predictions. Such efforts are possible after years of rapid progress, enabled by the greater availability of in vitro reagents, kinetic models, and ready access to PBPK software packages with ...
David Rodrigues   +2 more
wiley   +1 more source

Housing market connectedness and transmission of monetary policy

open access: yesEconomic Inquiry, Volume 63, Issue 3, Page 961-984, July 2025.
Abstract This paper investigates whether interconnectivity among local housing markets influences the effectiveness of the (United States) U.S. monetary transmission mechanism. We construct measures of housing market connectedness and employ a state‐dependent local projection method to estimate nonlinear impulse responses of macroeconomic variables to ...
Woo Suk Lee, Eunseong Ma
wiley   +1 more source

Decreased insulin dose-adjusted hemoglobin A1c in adults with cystic fibrosis-related diabetes treated with elexacaftor-tezacaftor-ivacaftor. [PDF]

open access: yesJ Clin Transl Endocrinol
Burnet E   +12 more
europepmc   +1 more source

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