Results 121 to 130 of about 172,685 (221)

Nanobody‐Mediated c‐MYC Degradation Inhibits Tumor Cell Progression

MedComm, Volume 7, Issue 4, April 2026.
A cell‐permeable nanobody strategy was developed to target the intrinsically disordered oncoprotein c‐MYC. A synthetic nanobody, M4, binds the central PEST region of c‐MYC (241–263) and promotes c‐MYC degradation by enhancing Thr58 phosphorylation. Conjugation of M4 to a cell‐penetrating peptide (CPP) generates CPM4, which efficiently accumulates in ...
Yuanyuan Xue, Hao Jiang, Zhaoyun Zong, Xiaolin Tian, Zelong Miao, Ting Li, Yali Wei, Haiteng Deng   +7 more
wiley   +1 more source

Del telégrafo a la app: la evolución y el estado actual de los prestadores de remesas desde los Estados Unidos hasta México, ca. 1980-2020*

El Trimestre Económico
Este artículo ofrece una primera aproximación a la evolución de la estructura y los participantes en el mercado de remesas del corredor entre los Estados Unidos y México.
Bernardo Bátiz Lazo, Ignacio González Correa   +1 more
doaj   +1 more source

Non‐Viral Cytokine‐Inducible SH2 Containing Protein Locus‐Specific Integrated Fibroblast Activation Protein Alpha‐Targeting Chimeric Antigen Receptor T Cells Achieve Potent Antitumor Efficacy in Glioblastoma

MedComm, Volume 7, Issue 4, April 2026.
FAPα is a dual target on glioblastoma cells and perivascular cells. Using a high‐affinity anti‐FAPα nanobody, we generated CISH‐KO FAPα‐CAR‐T cells via non‐viral CRISPR–Cas9 integration. These cells demonstrated enhanced proliferation and superior antitumor efficacy in patient‐derived organoids and orthotopic mouse models compared to conventional CAR‐T
Xin Dong, Yao Sun, Yuetong Guo, Jiao Wang, Fei Wang, Ziming Wang, Ruizhen Li, Fei Xie, Tingting Tan, Baijie Cheng, Ronghan Huang, Shu Zhang, Xiaotong Lin, Zhaoze Guo, Hubing Wu, Hao Wu, Xubiao Zhang, Guozhu Xie   +17 more
wiley   +1 more source

What Is a Polyolefin? A Critical Overview of Ethylene Copolymers Used as Solar Photovoltaic Module Encapsulants

Progress in Photovoltaics: Research and Applications, Volume 34, Issue 4, Page 367-395, April 2026.
Polyolefin encapsulants are gaining dominance in PV modules, yet confusion persists around PO, POE, and TPO definitions. This study clarifies terminology, reviews materials, and properties and proposes a taxonomy to improve understanding, communication, and reliability in solar module manufacturing.
Gernot Oreski, Chiara Barretta, Petra Christöfl, Paul Gebhardt, Karl‐Anders Weiß, David C. Miller, Soňa Uličná, Michael Kempe, Laura S. Bruckman, Alessandro Virtuani, Hengyu Li, Brian Habersberger, Jeff Munro, Kristof Proost, Marcel Kühne   +14 more
wiley   +1 more source

Political alignment in entrepreneurial teams: Homophily in venture formation and associations with startup success

Strategic Management Journal, Volume 47, Issue 4, Page 1161-1207, April 2026.
Abstract Research Summary We examine political affiliation's role in venture team formation and success. Using data from Crunchbase and L2 on 1125 US‐based startups, we investigate political homophily in team assembly and its association with startup outcomes.
Balázs Kovács, Tim Sels
wiley   +1 more source

Role of subjective norms in shaping entrepreneurial intentions among students

Economics and Business Review
In view of the inconsistency in prior research, the main goal of this analysis is to determine the influence of subjective norms on entrepreneurial intentions among Polish students. The secondary goal is to examine how these subjective norms are affected
Nessel Karolina, Kościółek Szczepan, Leśniak Anna   +2 more
doaj   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

Veterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes, António Caldeira Mendes, Susana Paula Alves, Vanessa Schmidt, Ana Filipa Bizarro, Marta Pinto, Hugo Pereira, Joana Marto, Ana Mafalda Lourenço   +8 more
wiley   +1 more source

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira, Wei Wang, Fernando Sanchez‐Valdez, Jihyun Lim, Brooke E. White, Camilla G. S. Souza, Rick L. Tarleton, Marcia C. Paes, Natalia P. A. Nogueira   +8 more
wiley   +1 more source

Enhancing propagation and purification efficiency of M13 bacteriophage for improved phage display applications. [PDF]

Biol Methods Protoc
Hossain MM, Yong F, Bansal V, Shukla R.
europepmc   +1 more source

Improved efficiency M13 cloning using electroporation

Nucleic Acids Research, 1989
Heery, David M., Dunican, L.Kieran
openaire   +4 more sources