Results 61 to 70 of about 136,659 (208)

A modular phage vector platform for targeted photodynamic therapy of Gram-negative bacterial pathogens

iScience, 2023
Summary: Growing antibiotic resistance has encouraged the revival of phage-inspired antimicrobial approaches. On the other hand, photodynamic therapy (PDT) is considered a very promising research domain for the protection against infectious diseases. Yet,
Annapaola Petrosino, Roberto Saporetti, Francesco Starinieri, Edoardo Sarti, Luca Ulfo, Luca Boselli, Andrea Cantelli, Andrea Morini, Suleman Khan Zadran, Giampaolo Zuccheri, Zeno Pasquini, Matteo Di Giosia, Luca Prodi, Pier Paolo Pompa, Paolo Emidio Costantini, Matteo Calvaresi, Alberto Danielli   +16 more
doaj   +1 more source

Screening polymeric ionic liquids for chromatography-based purification of bacteriophage M13 [PDF]

, 2021
M13 bacteriophage is a key instrument in phage display applications, as well as a possible antibacterial therapeutic agent due to its highly restrictive bacterial pathogenesis, and other applications. The traditional phage purification process is usually
Wagner, Alexandra, Gonçalves, João, Azevedo, A.M., Jacinto, M.J., Patinha, David J.S., Aires-Barros, M.R., Sá, Inês M., Willson, Richard C., Marrucho, Isabel M.   +8 more
core   +1 more source

A plug-and-play aptamer diagnostic platform based on linear dichroism spectroscopy

Frontiers in Chemistry, 2023
A plug-and-play sandwich assay platform for the aptamer-based detection of molecular targets using linear dichroism (LD) spectroscopy as a read-out method has been demonstrated.
Haydn A. Little, Haydn A. Little, Aysha Ali, Aysha Ali, Jake G. Carter, Jake G. Carter, Matthew R. Hicks, Timothy R. Dafforn, James H. R. Tucker   +8 more
doaj   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

An investigation of the properties of bacteriophage M13 and the implications for its large-scale bioprocessing [PDF]

, 2010
Bacteriophage are a diverse class of viruses that infect bacterial cells. As a result of over 60 years of molecular biology advances, bacteriophage today feature as candidates for vaccination, gene therapy, biomaterial and antibacterial purposes ...
Branston, S.D.
core  

Early stage evaluation of colon cancer using tungsten disulfide quantum dots and bacteriophage nano-biocomposite as an efficient electrochemical platform

Cancer Nanotechnology, 2022
Background Recently, biosensors have become popular analytical tools for small analytes due to their high sensitivity and wide analytical range. In the present work, development of a novel biosensing method based on tungsten disulfide quantum dots (WS2 ...
Ramin Pourakbari, Mehdi Yousefi, Balal Khalilzadeh, Mahsa Haddad Irani-nezhad, Alireza Khataee, Leili Aghebati-Maleki, Alireza Soleimanian, Amin Kamrani, Forough Chakari-Khiavi, Rozita Abolhasan, Morteza Motallebnezhad, Farhad Jadidi-Niaragh, Bahman Yousefi, Hossein Samadi Kafil, Mohammad Hojjat-Farsangi, Mohammad-Reza Rashidi   +15 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Mapping of Promoter Sites on the Genome of Bacteriophage M13 [PDF]

European Journal of Biochemistry, 1976
With the aid of transcription studies on restriction fragments of bacteriophage M13 DNA it has been demonstrated that at least eight promoter sites are located on the M13 genome. Five of these promoters initiate the synthesis of RNA chains which contain at their 5′‐terminal end pppG (G promoters), while the other three promoters initiate RNA chains ...
L, Edens, P, van Wezenbeek, N H, Konings, J G, Schoenmakers   +3 more
openaire   +2 more sources

Quantifying Structure‐Dependent Rigidity of 3D DNA Origami Boxes

Advanced Intelligent Systems, EarlyView.
We investigate the mechanical stability of a hollow 3D DNA origami box during assembly using liquid AFM imaging and finite element simulations. As structural completeness increases from flat sheets through intermediate assemblies to a closed box, rigidity improves.
Judith Zubia‐Aranburu, Reza Zadegan, Jens Vinge Nygaard, Jørgen Kjems, Ramesh Subramani, Mingdong Dong   +5 more
wiley   +1 more source

Scalable Separation and Purification of M13‐Bacteriophage‐Derived Particles Containing Artificial Single‐Stranded DNA Produced by Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner, Wiebke Winkler, Maximilian N. Honemann, Hendrik Dietz, Dirk Weuster‐Botz   +4 more
wiley   +1 more source