Results 81 to 90 of about 136,659 (208)
Development of a high-throughput method to screen novel antiviral materials.
Respiratory infectious diseases pose a serious threat worldwide, and novel antiviral materials are highly demanded. Photocatalytic nanoparticles have been developed to inhibit indirect transmission of pathogens by acting as surface coating materials ...
Makoto Nakakido +4 more
doaj +1 more source
Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira +7 more
wiley +1 more source
Transient self-templating assembly of M13 bacteriophage for enhanced biopiezoelectric devices
Many biogenic materials are hierarchically structured across several length scales. Attaining similar control over bottom-up assembly would allow for efficient synthesis of materials for enhanced electrical or energy generating devices. Here we developed
Kwang Heo +5 more
semanticscholar +1 more source
Chemical Modification of M13 Bacteriophage and Its Application in Cancer Cell Imaging
The M13 bacteriophage has been demonstrated to be a robust scaffold for bionanomaterial development. In this paper, we report on the chemical modifications of three kinds of reactive groups, i.e., the amino groups of lysine residues or N-terminal, the ...
Siqi Li (2283472) +8 more
core +1 more source
Hybrid Nanomaterial Complexes for Advanced Phage-guided Gene Delivery
Developing nanomaterials that are effective, safe, and selective for gene transfer applications is challenging. Bacteriophages (phage), viruses that infect bacteria only, have shown promise for targeted gene transfer applications.
Teerapong Yata +6 more
doaj +1 more source
Genetically encoded cyclic peptide libraries can be employed in cellular selection platforms to identify cyclic peptide inhibitors for therapeutic targets by directly selecting for desired biological activities. This review systematically summarizes representative studies and suggests future opportunities for using cellular selection for de novo cyclic
Linwei Yang +3 more
wiley +1 more source
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Expanded bed anion exchange adsorption for the purification of bacteriophage M13 [PDF]
The filamentous bacteriophage M13 can be used to display foreign peptides and proteins, allowing the construction of theurapeutic, vaccine development, diagnostic and technological tools of broad utility.
Shamsu Zaman, Mayamarni
core +1 more source
Bacteriophages, prokaryotic viruses, hold great potential in genetic engineering to open up new avenues for vaccine development. Our study aimed to establish engineered M13 bacteriophages expressing MAGE-A1 tumor peptides as a vaccine for melanoma ...
Nuša Brišar +5 more
doaj +1 more source
Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan +11 more
wiley +1 more source

