Results 51 to 60 of about 17,082 (154)

The Governance Gap: Democratizing Drug Development Through Decision Architecture

Clinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner, Nancy E. Martin, Danielle Smith, Eliza Kruger, Carl M.J. Kirkpatrick, Goonaseelan (Colin) Pillai, Katy Moore, Darrell Nix, Cristina Donini, Jakob P. Cramer, Edmundo Muniz, Natalia Muniz, Ernst Bos, Douglas McNair, Shyam Bhaskaran, Mark Sullivan, Dan Hartman   +16 more
wiley   +1 more source

The Impact of Digital HRM Implementation on Public Sector Performance: A Quantitative Analysis of Service Delivery Efficiency

ECONOMICS
This study investigates the extent to which digital HRM systems are implemented in public sector organizations and the assessment of the effectiveness of technology in enhancing organizational performance.
Amirova Aigerim, Iskendirova Saule, Daueshova Aliya, Zhanseitov Azamat, Abylasimov Murager   +4 more
doaj   +1 more source

Romanian Corporate Discourse Within the Context of Digital Transformation: A Multi-Methodological Longitudinal Analysis

Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice
This research investigates how the health crisis influenced digital technology adoption in the official discourse of Bucharest Stock Exchange companies by analysing annual financial reports from 2017 to 2024, divided into pre-pandemic (2017-2019) and ...
Dănescu Tatiana, Stejerean Roxana Maria
doaj   +1 more source

The EMA Qualification Opinion for CYP Inhibition‐Mediated Drug–Drug Interaction Predictions: Implications for PBPK Credibility Assessment in the Era of ICH M15

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical pharmacology and pharmacometrics teams are now being encouraged to implement the ICH M15 framework in drug development to support model‐informed decisions in regulatory submissions. Although model performance is an important component of model evaluation, regulatory confidence also depends on the intended context of use (CoU) and the ...
Karen Rowland Yeo, Sibylle Neuhoff, Oliver Hatley, Iain Gardner, Céline Brochot, Frédéric Y. Bois, Masoud Jamei   +6 more
wiley   +1 more source

Leveraging artificial intelligence to meet the sustainable development goals

Journal of Economics and Management
Aim/purpose – This study aims to identify the role of Artificial Intelligence (AI) in achieving the Sustainable Development Goals (SDGs), with specific reference to their targets, and to present good practices in this regard.
Ziemba Ewa Wanda, Duong Cong Doanh, Ejdys Joanna, Gonzalez-Perez Maria Alejandra, Kazlauskaitė Ruta, Korzynski Pawel, Mazurek Grzegorz, Paliszkiewicz Joanna, Stankevičienė Jelena, Wach Krzysztof   +9 more
doaj   +1 more source

Bridging Bystander Intervention and Workplace Inclusion: The Critical Role of Perceived Fairness, Support, and Safety

Journal of Organizational Behavior, EarlyView.
ABSTRACT Bystander intervention is widely assumed to foster workplace inclusion, yet no studies have directly examined this relationship. Through abductive qualitative analysis of 53 interviews across two contrasting organisations—a consulting firm and a remote mine site—we investigate how bystander intervention relates to workplace inclusion for ...
Laura Jennings, Kun Zhao, Liam Smith, Denise Goodwin, Nicholas Faulkner   +4 more
wiley   +1 more source

Digital Solution for Effective Management of Remote Work: The Case of Kazakhstan Railway

ECONOMICS
The following paper discusses the potential of digital solutions in controlling remote work at Kazakhstan Railways, focusing on the example of implementing the “Dilau Tracker” application.
Adilova Nazdana, Sultanbek Madiyar, Sarzhanov Dauren, Sładkowski Aleksander, Zhanseitov Azamat   +4 more
doaj   +1 more source

Reference Equations for Peak Nasal Inspiratory and Expiratory Flow: A Cross‐Sectional Study

The Laryngoscope, EarlyView.
This study developed reference equations for peak nasal inspiratory flow (PNIF) and peak nasal expiratory flow (PNEF) in clinically healthy adults using sex, height, and weight. PNIF demonstrated lower residual variability and more stable model performance than PNEF, supporting its potential as a complementary tool for individualized interpretation of ...
Gardênia Maria Martins de Oliveira, Gabriel Zorello Laporta, Joao Paulo Duarte Sabiá, Joao Marcos Ferreira, Edigê Felipe de Sousa Santos, Rodrigo Daminello Raimundo   +5 more
wiley   +1 more source

Exploring biofiber properties and their influence on biocomposite tensile properties

Polymer International, EarlyView.
The study measured the physical, flow and chemical properties of 10 biofibers. It characterized the tensile properties of derived biocomposites and linked them using regression models, showing robust predictive performance. Abstract Biofibers serve as effective reinforcements for neat polylactic acid (PLA) in biocomposites, offering an attractive ...
Oluwafemi A. Oyedeji, Jocelyn Hess, Xianhui Zhao, Luke Williams, Rachel Emerson, Erin Webb   +5 more
wiley   +1 more source

Exploring Analytic Hierarchy Process (AHP) Applications in Banking: A Bibliometric Study

Business Systems Research
A bibliometric analysis was conducted to investigate the prevalence of the Analytic Hierarchy Process (AHP) in academic studies, revealing it to be one of the most widely used methods in multi-criteria decision-making.
Mijoč Ivo, Briš Martina, Karačić Domagoj   +2 more
doaj   +1 more source