Results 231 to 240 of about 22,962 (264)

Autoradiographic localization of peripheral M1 muscarinic receptors using [3H]pirenzepine

Brain Research, 1986
A novel antimuscarinic agent, pirenzepine, has been proposed to distinguish at least two subtypes of muscarinic receptor. M1 receptors have been designated as those displaying a high affinity for pirenzepine. Both functional and binding studies have revealed a prevalence of M1 receptors in sympathetic ganglia while autonomic effector tissues have only ...
N J, Buckley, G, Burnstock
openaire   +2 more sources

Disinhibition in the rat septum mediated by M1 muscarinic receptors

Brain Research, 1988
Acetylcholine (ACh) has been documented as an important central neurotransmitter. We have investigated the actions of ACh within the dorsolateral septal nucleus of the rat to examine its actions within this nucleus, specifically how it may interact to modulate the inhibitory action of gamma-aminobutyric acid (GABA), the known inhibitory transmitter in ...
H, Hasuo, J P, Gallagher, P, Shinnick-Gallagher   +2 more
openaire   +2 more sources

Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice

Nature Neuroscience, 2002
Blockade of cholinergic neurotransmission by muscarinic receptor antagonists produces profound deficits in attention and memory. However, the antagonists used in previous studies bind to more than one of the five muscarinic receptor subtypes. Here we examined memory in mice with a null mutation of the gene coding the M1 receptor, the most densely ...
Stephan G, Anagnostaras, Geoffrey G, Murphy, Susan E, Hamilton, Scott L, Mitchell, Nancy P, Rahnama, Neil M, Nathanson, Alcino J, Silva   +6 more
openaire   +2 more sources

Muscarinic M1-Receptor-Antagonists in Health and Disease

1985
Muscarinic antagonists are widely used in clinical medicine as inhibitors of secretory and motor functions of the gastrointestinal (GI) tract. Atropine as a potent muscarinic inhibitor produces considerable side effects on the heart, accommodation, and saliva secretion.
P. C. Lederer, R. Thiemann, A. Ellermann, J. Radeck, G. Lux   +4 more
openaire   +1 more source

Muscarinic M1-Receptor Agonists

CNS Drugs, 1995
Neal R. Cutler, John J. Sramek
openaire   +1 more source

Muscarinic analgesia is mediated by non-M1 muscarinic receptors

Life Sciences, 1993
M.D.B. Swedberg, M.J. Sheardown, P. Sauerberg, P. Olesen, P.D. Suzdak, H.E. Shannon, F.P. Bymaster, J.S. Ward, C.H. Mitch, D.O. Calligaro   +9 more
openaire   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Victoria Metaxa   +2 more
exaly  

Breast Cancer Statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Hyuna Sung, Kimberly D Miller, Rebecca L Siegel   +2 more
exaly