Results 51 to 60 of about 4,384,622 (335)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

M2 macrophages in metabolism [PDF]

Diabetology International, 2016
Adipose tissue not only functions as the major energy-storing tissue, but also functions as an endocrine organ that regulates systemic metabolism by releasing various hormones called adipokines. Macrophages play a critical role in maintaining adipocyte health in a lean state and in remodeling during the progression of obesity.
Shiho, Fujisaka, Isao, Usui, Allah, Nawaz, Akiko, Takikawa, Tomonobu, Kado, Yoshiko, Igarashi, Kazuyuki, Tobe   +6 more
openaire   +2 more sources

Supergravity Solutions of Two M2 Branes

, 2013
We present an exact analytic class of solutions for a system of two membranes in eleven-dimensional supergravity. One brane in the system is completely localized along the overall and relative transverse coordinates while the other brane in the system is
Ghezelbash, A. M., Oraji, R.
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Half-BPS M2-brane orbifolds [PDF]

, 2010
Smooth Freund-Rubin backgrounds of eleven-dimensional supergravity of the form AdS_4 x X^7 and preserving at least half of the supersymmetry have been recently classified.
de Medeiros, Paul, Figueroa-O'Farrill, José   +1 more
core   +2 more sources

M2-Branes and Fano 3-folds

, 2011
A class of supersymmetric gauge theories arising from M2-branes probing Calabi-Yau 4-folds which are cones over smooth toric Fano 3-folds is investigated.
, Aharony O Bergman O Jafferis D L Maldacena J, Amariti A Forcella D Girardello L Mariotti A, Amihay Hanany, Bagger J, Balasubramanian V Berglund P Garcia-Etxebarria I, Batyrev V V, Batyrev V V, Beasley C E, Benishti N He Y H Sparks J, Benvenuti S, Benvenuti S, Blumenhagen R, Blumenhagen R Grimm T W Jurke B Weigand T, Broomhead N, Butti A, Butti A, Conlon J P, Davey J, Davey J Hanany A Mekareeya N Torri G, Davey J Hanany A Mekareeya N Torri G, Davey J Hanany A Pasukonis J, Feng B, Feng B, Feng B, Feng B, Feng B, Feng B, Forcella D, Forcella D, Forcella D, Forcella D Hanany A Zaffaroni A, Franco S, Franco S, Franco S, Franco S, Franco S, Franco S Hanany A He Y H Kazakopoulos P, Futaki A, Giuseppe Torri, Gray J, Gustavsson A, Gustavsson A, Hanany A, Hanany A, Hanany A, Hanany A He Y H, Hanany A He Y H, Hanany A Kennaway K D, Hanany A Mekareeya N Torri G, Hanany A Vegh D Zaffaroni A, Hanany A Zaffaroni A, Hewlett J He Y H, Iskovskih V A, Iskovskih V A, John Davey, Klebanov I R Torri G, Kollar J, Kreuzer M Nill B, Malyshev D, Martelli D Sparks J, Mori S, Mori S, Noppadol Mekareeya, Petrini M Zaffaroni A, Taki M, Ueda K Yamazaki M, Van Raamsdonk M, Verlinde H, Øbro M   +69 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Simple Conceptual Model for the Heat Induced Circulation over Northern South America and Meso-America

Atmosphere, 2020
The physical description of the atmosphere’s general circulation over Northern South America and Meso-America deserves a more comprehensive explanation. This work presents the Pacific coast of Colombia as the rainiest place on Earth, with annual rainfall
Julián David Rojo Hernández, Óscar José Mesa   +1 more
doaj   +1 more source

A Massive Study of M2-brane Proposals [PDF]

, 2008
We test the proposals for the worldvolume theory of M2-branes by studying its maximally supersymmetric mass-deformation. We check the simplest prediction for the mass-deformed theory on N M2-branes: that there should be a set of discrete vacua in one-to ...
Gomis, Jaume, Rodriguez-Gomez, Diego, Van Raamsdonk, Mark, Verlinde, Herman   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source