Results 21 to 30 of about 23,917 (146)
N-glycosylation of infectious bronchitis virus M41 spike determines receptor specificity
Infection of chicken coronavirus infectious bronchitis virus (IBV) is initiated by binding of the viral heavily N-glycosylated attachment protein spike to the alpha-2,3-linked sialic acid receptor Neu5Ac. Previously, we have shown that N-glycosylation of recombinantly expressed receptor binding domain (RBD) of the spike of IBV-M41 is of critical ...
Bouwman, K.M. +7 more
openaire +5 more sources
Murine Cytomegalovirus m41 Open Reading Frame Encodes a Golgi-Localized Antiapoptotic Protein [PDF]
ABSTRACT Viruses have evolved various strategies to prevent premature apoptosis of infected host cells. Some of the viral genes mediating antiapoptotic functions have been identified by their homology to cellular genes, but others are structurally unrelated to genes of known function.
Wolfram, Brune +2 more
openaire +2 more sources
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang +21 more
wiley +1 more source
Amphritea atlantica gen. nov., sp. nov., a gammaproteobacterium from the Logatchev hydrothermal vent field [PDF]
A novel Gram-negative, motile, aerobic rod-shaped bacterium was isolated from a Bathymodiolus sp. specimen collected from the Logatchev hydrothermal vent field at the Mid-Atlantic Ridge.
Gärtner, Andrea +2 more
core +1 more source
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak +7 more
wiley +1 more source
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff +3 more
wiley +1 more source
Productive replication of nephropathogenic infectious bronchitis virus in peripheral blood monocytic cells, a strategy for viral dissemination and kidney infection in chickens [PDF]
In the present study, the replication kinetics of nephropathogenic (B1648) and respiratory (Massachusetts-M41) IBV strains were compared in vitro in respiratory mucosa explants and blood monocytes (KUL01(+) cells), and in vivo in chickens to understand ...
Avalakuppa Papi Reddy, Vishwanatha Reddy +5 more
core +3 more sources
Abstract High total phosphorus (TP) concentrations in freshwater such as streams, rivers, and lakes remain a global issue, causing eutrophication and poor ecological conditions. We extracted annual flow‐weighted TP concentration data (N = 3144) from 207 monitored Danish headwater streams (catchment area < 50 km2) during the period 1990–2019 as the ...
Brian Kronvang +4 more
wiley +1 more source
Large non-Gaussianity from multi-brid inflation
A model of multi-component hybrid inflation, dubbed multi-brid inflation, in which various observable quantities including the non-Gaussianity parameter f_{NL} can be analytically calculated was proposed recently.
Alabidi +27 more
core +1 more source
SO(4) Symmetry of the Transfer Matrix for the One-Dimensional Hubbard Model
The SO(4) invariance of the transfer matrix for the one-dimensional Hubbard model is clarified from the QISM (quantum inverse scattering method) point of view. We demonstrate the SO(4) symmetry by means of the fermionic R-matrix, which satisfy the graded
Affleck I +30 more
core +2 more sources

