Results 71 to 80 of about 2,347 (191)

Kronik Hepatit B Enfeksiyonunda Hepatik Hasar Düzeyinin Öngörülmesinde M30 ve M65 Antijen Düzeylerinin Etkinliği

, 2018
Background and Aims: We aimed to determine the utility of M30and M65 antigen concentration levels for predicting hepatic injury inchronic hepatitis B disease.
Sezgin VATANSEVER, Mustafa ÇELİK, Belkis ÜNSAL, Çelik, Mustafa, Altay KANDEMİR, Kandemir, Altay, Ünsal, Belkıs, Vatansever, Sezgin   +7 more
core   +1 more source

Tumor cell-collagen interactions: Identification and semi-quantitative evaluation of selectively-expressed genes by combination of differential display- and multiplex-PCR

Biological Procedures Online, 2003
It is widely acknowledged that the presence of extracellular matrix components as substrates can drastically modulate the phenotype and gene expression of cultured cells, including tumor cells. A number of published reports indicated that substrates made
Sirchia Rosalia, Ciacciofera Valentina, Luparello Claudio   +2 more
doaj   +1 more source

Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis

British Journal of Pharmacology, Volume 182, Issue 22, Page 5647-5669, November 2025.
Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic, Sara Campinoti, Lai Wei, Bruna Almeida, Sergio Francesco Bozzano, Ramin Amiri, Nicola Harris, Omolola Ajayi, Tsin Shue Koay, Caoimhe Kerins, Fiona N. Kenny, Ane Zamalloa, Lissette Adofina, Rosa Miquel, Yoh Zen, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Camilla Luni, Eileen Gentleman, Tanya Shaw, Daren Ure, Shilpa Chokshi, Luca Urbani, Elena Palma   +24 more
wiley   +1 more source

Cytokeratin 18 for chemotherapy efficacy in gastric cancer [PDF]

, 2015
WOS: 000366737700005Cytokeratin 18 (CK18) is the major component of intermediate filaments in epithelial cells and released into the blood in either intact (M65) or caspase-cleaved forms (M30) during apoptotic and necrotic cell death.
Bilici, Ahmet
core   +1 more source

Non-invasive diagnosis of alcohol-related steatohepatitis in patients ongoing alcohol withdrawal based on cytokeratin 18 and transient elastography

, 2023
International audienceBACKGROUND AND AIMS: The diagnosis of alcoholic steatohepatitis (ASH) is based on liver biopsy, which is costly and invasive with non-negligible morbidity.
Jean François Viel, Chalin, Arnaud, Sophie Michalak, Ahmad Ousmen, Bardou-Jacquet, Edouard, Turlin, Bruno, Samson, Michel, Legros, Ludivine, Edouard Bardou‐Jacquet, Mueller, Sebastian, Michel Samson, Viel, Jean François, Sebastian Mueller, Ousmen, Ahmad, Mueller, Johannes, Bruno Turlin, Moirand, Romain, Arnaud Chalin, Johannes Mueller, Romain Moirand, Ludivine Legros, Michalak, Sophie   +21 more
core   +1 more source

Bis[3-chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinato]nickel(II) tetrahydrate

Acta Crystallographica Section E, 2008
In the title complex, [Ni(C11H9ClN3O2)2]·4H2O, the Ni atom is coordinated by four N atoms and two O atoms derived from two tridentate 3-chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinate ligands.
Kai Zhao, Xian-Hong Yin, Yu Feng, Jie Zhu, Cui-Wu Lin   +4 more
doaj   +1 more source

A Phase 2a Trial of Myeloperoxidase Inhibitor Mitiperstat in Non‐Cirrhotic Metabolic Dysfunction‐Associated Steatohepatitis

Liver International, Volume 45, Issue 11, November 2025.
ABSTRACT Background and Aims Neutrophil myeloperoxidase is involved in different inflammatory diseases, including metabolic dysfunction‐associated steatohepatitis (MASH). Mitiperstat is a highly potent myeloperoxidase inhibitor. This phase 2a clinical trial evaluated the efficacy, safety, pharmacokinetics, and pharmacodynamics of mitiperstat in ...
Javier Armisen, Armando Flor, John Eriksson, Karin Nelander, Chandrali S. Bhattacharya, Mikael Sunnåker, Debra Carter, Monika Trebski, Emma Gårdmark, Malin Aurell, Carl Whatling, Benjamin Challis, Umberto Vespasiani‐Gentilucci, on behalf of the COSMOS Investigators, Alejandra Camino, Fernando Gruz, Luis Colombato, Maria Anders, Matias Bori, Natalia Cluigt, Astrid Naver, Henning Grønbæk, Jacob Brodersen, Mette Lauridsen, Shaista Rashid, Alessandra Mangia, Alessio Aghemo, Anna Fracanzani, Elisabetta Bugianesi, Emanuele Bosi, Gaetano Serviddio, Luca Miele, Maurizio Russello, Alma Ladrón de Guevara Cetina, Fernando Grover Páez, Israel Olvera Alvarez, Ricardo Macías Rodríguez, Hans Lannerstedt, Rasmus Goll, João Raposo, Albert Lecube Torello, Alfonso Soto Gonzalez, Antonio Olveira Martín, Esteban Jódar, Francisco José Tinahones Madueño, Javier Crespo García, Moisés Diago Madrid, Mattias Ekstedt, Amit Bhanvadia, Duane Anderson, Linda DiTeodoro, Mindie Nguyen, Naim Alkhouri, Niaz Ausaf, Peter Wayne, Rizwana Mohseni, Sam Moussa, Yaneicy Gonzalez Rojas   +57 more
wiley   +1 more source

Diiodido(1,10-phenanthroline-κ2N,N′)platinum(II)

Acta Crystallographica Section E, 2010
In the title complex, [PtI2(C12H8N2)], the Pt2+ ion is four-coordinated in a slightly distorted square-planar environment by two N atoms of the chelating 1,10-phenanthroline ligand and two iodide ions.
Kwang Ha
doaj   +1 more source

A New Lactone from Chaetomiurn globosum Strain M65 that Inhibits the Motility of Zoospores

, 2016
In a search for endophytes from medicinal plants of Bangladesh, we isolated the M65 fungal strain from the fruit of Azadirachta indica. Following chemical screening, chromatographic purification of the culture extract of strain M65 led to the isolation ...
Mondol, Muhammad Abdul Mojid, Islam, Mohammad Tofazzal, Schueffler, Anja, Laatsch, Hartmut, Farthouse, Jannatul   +4 more
core   +1 more source

Diaqua[N,N′-bis(2-pyridylmethylene)propane-1,3-diamine]manganese(II) dibromide–aquabromido[N,N′-bis(2-pyridylmethylene)propane-1,3-diamine]manganese(II) bromide–dibromido[N,N′-bis(2-pyridylmethylene)propane-1,3-diamine]manganese(II) (1/2/1)

Acta Crystallographica Section E, 2009
There are three different MnII complexes in the asymmetric unit of the title compound, [Mn(C15H16N4)(H2O)2]Br2·2{[MnBr(C15H16N4)(H2O)]Br}·[MnBr2(C15H16N4)].
In-Chul Hwang, Kwang Ha
doaj   +1 more source