Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Incidence and Management Trends in Advanced Head and Neck Non-Melanoma Skin Cancer in Ontario. [PDF]
Yeung KD +6 more
europepmc +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Optimizing identification of major adverse limb and cardiovascular events among adults with peripheral artery disease in administrative data. [PDF]
Nassereldine H +5 more
europepmc +1 more source
AMDS and quantum AMDS Constacyclic codes of length $4p^ς$ over $\mathbb{F}_{{p}^{m}}$ [PDF]
Manasa J +2 more
openalex
Repeated-Root Constacyclic Codes of Length $3p^s$ over the Finite Non-Chain Ring $\frac{\mathbb{F}_{p^m}[u, v]}{\langle u^2, v^2, uv-vu\rangle}$ and their Duals [PDF]
Acharya, Divya +2 more
openalex +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Ultrasound Procedure Codes Enable Timely Surveillance of Ongoing Pregnancies: A Nationwide Population-Based Register Study. [PDF]
Greve-Isdahl M +7 more
europepmc +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source

