Results 81 to 90 of about 75,024 (314)

First description of the female of the theridiid spider Robertus golovatchi (Araneae: Theridiidae) [PDF]

open access: yes, 2012
The female of Robertus golovatchi Eskov, 1987 is described for the first time from Abkhazia and the male is also figured. The female is compared to another species known from the Caucasus R.
Kovblyuk, Mykola M., Marusik, Yuri M.
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Preparation of Mealybugs (Hemiptera: Pseudococcidae) for Genetic Characterization and Morphological Examination. [PDF]

open access: yes, 2015
Mealybugs (Hemiptera: Pseudococcidae) are economically significant agricultural pests on many different crops. Because of their small size and lack of easily visible characters for identification, determination of their taxonomic status is difficult and ...
Bahder, BW   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Análise de processos alternativos na preparação de esqueletos para uso didático = Analysis of alternative processes of skeleton preparation for educational uses

open access: yesActa Scientiarum: Biological Sciences, 2008
Laboratórios de Zoologia em Instituições de Pesquisa e Ensino têmdemonstrado grande demanda por peças anatômicas para utilização em aulas práticas. No entanto, embora a bibliografia voltada para este tema não seja escassa, são raras as análises das ...
Márcio José da Silveira   +2 more
doaj  

Mineral composition through soil-wine system of portuguese vineyards and its potential for wine traceability [PDF]

open access: yes, 2018
The control of geographic origin is one of a highest priority issue regarding traceability and wine authenticity. The current study aimed to examine whether elemental composition can be used for the discrimination of wines according to geographical ...
Brady   +13 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Foam dressings: a review of the literature and evaluation of fluid-handling capacity of four leading foam dressings [PDF]

open access: yes, 2015
Posnett and Franks (2008) have calculated that 200,000 people in the UK have a chronic wound, with an estimated treatment cost of between £2.3 billion and £3.1 billion per year.
Atkin, Leanne   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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