Results 41 to 50 of about 4,445 (267)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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TO SELECTION OF TECHNOLOGICAL SCHEME OF SOFTENING HEAT TREATMENT FOR HIGH CHROMIUM CAST IRON
Nauka ta progres transportu, 2014 Purpose. High chromium cast irons with austenitic matrix have low machinability. The aim of work is search of new energy-saving modes of preliminary softening heat treatment enhancing the machinability of castings by forming an optimum microstructure ...
V. G. Efremenko +4 more
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Vibration Sensor Monitoring of Nickel-Titanium Alloy Turning for Machinability Evaluation
Sensors, 2017 Nickel-Titanium (Ni-Ti) alloys are very difficult-to-machine materials causing notable manufacturing problems due to their unique mechanical properties, including superelasticity, high ductility, and severe strain-hardening. In this framework, the aim of
Tiziana Segreto +3 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Machine in the Text, and the Text in the Machine
Digital Humanities Quarterly, 2010 The Machine in the Text, and the Text in the Machine is a review essay on Electronic Literature: New Horizons for the Literary (Notre Dame, IN: University of Notre Dame, 2008), by N. Katherine Hayles, and Mechanisms: New Media and the Forensic Imagination (Cambridge, Mass.: MIT Press, 2008), by Matthew G. Kirschenbaum.
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Journal of Materials Research and TechnologyFor titanium alloy parts prepared by selective laser melting (SLM), post-treatment operation is usually utilized to meet the needed surface accuracy and dimensional tolerances.
Zhongwei Chen +5 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Iranian Journal of Materials Science and Engineering, 2019 Relations between the microstructure, mechanical properties and machinability of as-cast 65Cu-35Zn brass with various amounts of Al from 0 to 4.72 and Si from 0 to 3.62 wt% were investigated. Both Si and Al initially enhanced the UTS and toughness of the
M. Adineh +2 more
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