Results 41 to 50 of about 4,483 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Effect of heat treatment on the anisotropic machinability of additive manufactured titanium alloys in micro-milling

open access: yesJournal of Materials Research and Technology
For titanium alloy parts prepared by selective laser melting (SLM), post-treatment operation is usually utilized to meet the needed surface accuracy and dimensional tolerances.
Zhongwei Chen   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect OF SI and AL on the Microstructure, Mechanical Properties and Machinability of 65CU-35ZN Brass

open access: yesIranian Journal of Materials Science and Engineering, 2019
Relations between the microstructure, mechanical properties and machinability of as-cast 65Cu-35Zn brass with various amounts of Al from 0 to 4.72 and Si from 0 to 3.62 wt% were investigated. Both Si and Al initially enhanced the UTS and toughness of the
M. Adineh   +2 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Study of machinability of VP 100 steel with different levels of titanium in end milling operations

open access: yesActa Scientiarum: Technology, 2015
During the manufacture of a mould, machining is certainly the most important process. The composition required to provide important properties in the steels used, such as hardness, wear and corrosion resistance, results in a low machinability has ...
Jean Robert Pereira Rodrigues   +5 more
doaj   +1 more source

The Machine in the Text, and the Text in the Machine

open access: yesDigital Humanities Quarterly, 2010
The Machine in the Text, and the Text in the Machine is a review essay on Electronic Literature: New Horizons for the Literary (Notre Dame, IN: University of Notre Dame, 2008), by N. Katherine Hayles, and Mechanisms: New Media and the Forensic Imagination (Cambridge, Mass.: MIT Press, 2008), by Matthew G. Kirschenbaum.
openaire   +3 more sources

Machine behaviour [PDF]

open access: yesNature, 2019
Machines powered by artificial intelligence increasingly mediate our social, cultural, economic and political interactions. Understanding the behaviour of artificial intelligence systems is essential to our ability to control their actions, reap their benefits and minimize their harms.
Iyad Rahwan   +22 more
openaire   +13 more sources

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