Results 51 to 60 of about 4,445 (267)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Study of machinability of VP 100 steel with different levels of titanium in end milling operations
Acta Scientiarum: Technology, 2015 During the manufacture of a mould, machining is certainly the most important process. The composition required to provide important properties in the steels used, such as hardness, wear and corrosion resistance, results in a low machinability has ...
Jean Robert Pereira Rodrigues +5 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Machine-to-Machine Communications for Healthcare
Journal of Computing Science and Engineering, 2012 Machine-to-machine communications for healthcare is emerging for the benefit of humans. In addition to novel medium access, we provide a systematic view to look for ways to develop technology to accomplish this goal, and a thorough vision toward effective system and network design.
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Journal of Manufacturing and Materials ProcessingAustenitic stainless steels, such as 304 and 304L, are extensively utilized in diverse industries due to their favorable properties, including biocompatibility, high durability, ductility, toughness at cryogenic temperatures, and excellent corrosion ...
Bahman Azarhoushang +3 more
doaj +1 more source
A Comparative Study on Cutting Tool Performance in High-Speed Face-Milling of Hardened Tool Steels [PDF]
Archives of Metallurgy and MaterialsIn this study cutting speeds and tool life constants for seven different cutting tools are investigated while high-speed face milling of four different much used hardened tool steels.1.2379 and 1.2080 cold-work tool steels, 1.2344 hot-work tool steel and
Ali O. Er, E. Aslan
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source