Results 71 to 80 of about 28,649 (315)

Machine-to-Machine Communications for Healthcare

open access: yesJournal of Computing Science and Engineering, 2012
Machine-to-machine communications for healthcare is emerging for the benefit of humans. In addition to novel medium access, we provide a systematic view to look for ways to develop technology to accomplish this goal, and a thorough vision toward effective system and network design.
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Design of ultraprecision machine tools with application to manufacturing of miniature and micro components [PDF]

open access: yes, 2005
Currently the underlying necessities for predictability, producibility and productivity remain big issues in ultraprecision machining of miniature/microproducts.
Chen   +20 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Effect OF SI and AL on the Microstructure, Mechanical Properties and Machinability of 65CU-35ZN Brass

open access: yesIranian Journal of Materials Science and Engineering, 2019
Relations between the microstructure, mechanical properties and machinability of as-cast 65Cu-35Zn brass with various amounts of Al from 0 to 4.72 and Si from 0 to 3.62 wt% were investigated. Both Si and Al initially enhanced the UTS and toughness of the
M. Adineh   +2 more
doaj  

The Effects of Alloy Composition and Surface Integrity on the Machinability of Austenitic Stainless Steels 304 and 304L

open access: yesJournal of Manufacturing and Materials Processing
Austenitic stainless steels, such as 304 and 304L, are extensively utilized in diverse industries due to their favorable properties, including biocompatibility, high durability, ductility, toughness at cryogenic temperatures, and excellent corrosion ...
Bahman Azarhoushang   +3 more
doaj   +1 more source

A Comparative Study on Cutting Tool Performance in High-Speed Face-Milling of Hardened Tool Steels [PDF]

open access: yesArchives of Metallurgy and Materials
In this study cutting speeds and tool life constants for seven different cutting tools are investigated while high-speed face milling of four different much used hardened tool steels.1.2379 and 1.2080 cold-work tool steels, 1.2344 hot-work tool steel and
Ali O. Er, E. Aslan
doaj   +1 more source

Pembangunan dan keberkesanan kit penyongsang dalam proses pengajaran dan pembelajaran (PDP) di kolej vokasional [PDF]

open access: yes, 2019
Pembangunan Alat Bahan Bantu Mengajar (ABBM) untuk menggalakkan guru menggunakan Kit Penyongsang dalam proses pengajaran dan pembelajaran (PdP). Kajian ini bertujuan untuk membangun dan menguji keberkesanan Kit Penyongsang dalam PdP di Kolej Vokasional ...
Abdullah, Nurul Aida Suhaila
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Converting a CAD Model into a Manufacturing Model for the Components Made of a Multiphase Perfect Material [PDF]

open access: yes, 2004
To manufacture the component made of a multiphase perfect material (including homogeneous and multi heterogeneous materials), it CAD model should be processed and converted into layered manufacturing model for further transformation of numerical ...
Chen, Ke-Zhang, Feng, Xin-An, Zhu, Feng
core   +1 more source

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