Results 71 to 80 of about 1,074,730 (288)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Context Aware Adaptable Applications - A global approach [PDF]

, 2009
Actual applications (mostly component based) requirements cannot be expressed without a ubiquitous and mobile part for end-users as well as for M2M applications (Machine to Machine).
Dalmau, Marc, Laplace, Sophie, Roose, Philippe   +2 more
core   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

OCRIS : online catalogue and repository interoperability study. Final report [PDF]

, 2009
The aims and objectives of OCRIS were to: • Survey the extent to which repository content is in scope for institutional library OPACs, and the extent to which it is already recorded there; • Examine the interoperability of OPAC and repository software ...
Birrell, Duncan, Dunsire, Gordon, Menzies, Kathleen   +2 more
core  

A Scalable Hybrid MAC Protocol for Massive M2M Networks

, 2013
In Machine to Machine (M2M) networks, a robust Medium Access Control (MAC) protocol is crucial to enable numerous machine-type devices to concurrently access the channel.
Cao, Xianghui, Chen, Jiming, Liu, Yi, Yuen, Chau   +3 more
core   +1 more source

Cross platform social media analysis for mental health detection

Discover Mental Health
While mental health challenges have increasingly become a major concern globally, social media platforms provide tremendous data for, among others, analyzing emotional and behavioral patterns.
Kanishka Bhatt, Ashwini Kumar Singh, Priyank Pandey, Ankit Vishnoi, Preeti Narooka   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Computer intelligence based model for mental health detection among Indian farming communities

Scientific Reports
Mental health challenges among Indian farmers are a critical yet under reviewed public health problem, especially in rural areas where access to men’s health professionals is limited.
Jyoti Agarwal, Sachin Sharma, Parul Madan, Ankit Vishnoi, Preeti Narooka   +4 more
doaj   +1 more source

Evaluating Binary Serialization Protocols for IoT/M2M Applications over Hybrid Terrestrial and Non-Terrestrial Networks

Telecom
The rapid growth of Internet of Things (IoT) deployments in hybrid terrestrial/non-terrestrial networks (TN/NTN) faces a major bottleneck: the verbosity of standard data formats like JSON.
Natesh Kumar, Mariano Falcitelli, Francesco Kotopulos De Angelis, Paolo Pagano, Sandro Noto   +4 more
doaj   +1 more source

Toward a M2M-Based Internet of Vehicles Framework for Wireless Monitoring Applications

IEEE Access, 2018
The Internet of Vehicles (IoV) has become an attractive research topic in the fields of communication networks and information processing due to its wide range of potential applications, including public transportation management, road traffic ...
Fei Ding, Ruoyu Su, En Tong, Dengyin Zhang, Hongbo Zhu, Mohamed Wahab Mohamed Ismail   +5 more
doaj   +1 more source