Results 101 to 110 of about 8,117,786 (302)
EXTENDED TECHNICAL INSPECTION FOR PATH OF ROLLING FROM M5A COAL REMOVAL MACHINE [PDF]
Journal of Research and Innovation for Sustainable Society, 2020 This path of rolling is carried out on longitudinal ties of reinforced concrete and is formed from the superstructure 49 by 15 m length, fixed to the metal plates 49 with the clamping indirect type.The way of rolling has 680 m of which is operated on a
Alin STĂNCIOIU
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Metaphysical Primitives: Machines and Assemblages in Deleuze, DeLanda, and Bryant
Open Philosophy, 2020 Some variants of Object-Oriented Ontology define entities in terms of their powers. Such variants are rooted in Gilles Deleuze and Félix Guattari’s theory of “machinic assemblages”.
Kleinherenbrink Arjen
doaj +1 more source
Cold Start for the Green Innovation Machine [PDF]
This Policy Contribution accompanies the Policy Brief, Â?No Green Growth Without InnovationÂ?. Written by Senior Non-Resident Fellow Philippe Aghion, Senior Resident Fellow Reinhilde Veugelers and Researcher Clément Serre, this paper discusses the state ...
Clément Serre +2 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Projet d'une philosophie extra-ordinaire
Methodos, 2010 The aim of this paper is to discuss a philosophical method based on narrative fiction. I attempt to make systematic, and to give a foundation to, the use of narrative fictions in philosophy.
Pierre Cassou-Noguès
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Frontiers in Bioengineering and Biotechnology, 2014 There’s a time to be born, and a time to die; a time to break down, and a time to build up; a time to weep, and a time to laugh; a time to keep silence, and a time to speak… (Ecclesiastes 3, 2-7). There was a time when automata were designed like clocks.
Danilo Emilio De Rossi +1 more
doaj +1 more source
User Research of a Voting Machine: Preliminary Findings and Experiences [PDF]
, 2007 This paper describes a usability study of the Nedap voting machine in the Netherlands. On the day of the national elections, 566 voters participated in our study immediately after having cast their real vote.
Gosselt, Jordy +2 more
core +2 more sources