Results 81 to 90 of about 5,351,341 (268)

Single Phase Current-Source Active Rectifier for Traction: Control System Design and Practical Problems

open access: yesAdvances in Electrical and Electronic Engineering, 2006
This research has been motivated by industrial demand for single phase current-source active rectifier dedicated for reconstruction of older types of dc machine locomotives. This paper presents converters control structure design and simulations.
Jan Michalik   +2 more
doaj  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

EXTENDED TECHNICAL INSPECTION FOR PATH OF ROLLING FROM M5A COAL REMOVAL MACHINE [PDF]

open access: yesJournal of Research and Innovation for Sustainable Society, 2020
This path of rolling is carried out on longitudinal ties of reinforced concrete and is formed from the superstructure 49 by 15 m length, fixed to the metal plates 49 with the clamping indirect type.The way of rolling has 680 m of which is operated on a
Alin STĂNCIOIU
doaj  

The State Of Play: A Notional Machine for Learning Programming [PDF]

open access: yes, 2014
Comprehension of programming and programs is known to be a difficult task for many beginning students, with many computing courses showing significant drop out and failure rates.
Berry, Michael, Kölling, Michael
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Metaphysical Primitives: Machines and Assemblages in Deleuze, DeLanda, and Bryant

open access: yesOpen Philosophy, 2020
Some variants of Object-Oriented Ontology define entities in terms of their powers. Such variants are rooted in Gilles Deleuze and Félix Guattari’s theory of “machinic assemblages”.
Kleinherenbrink Arjen
doaj   +1 more source

Cold Start for the Green Innovation Machine [PDF]

open access: yes
This Policy Contribution accompanies the Policy Brief, Â?No Green Growth Without InnovationÂ?. Written by Senior Non-Resident Fellow Philippe Aghion, Senior Resident Fellow Reinhilde Veugelers and Researcher Clément Serre, this paper discusses the state ...
Clément Serre   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Projet d'une philosophie extra-ordinaire

open access: yesMethodos, 2010
The aim of this paper is to discuss a philosophical method based on narrative fiction. I attempt to make systematic, and to give a foundation to, the use of narrative fictions in philosophy.
Pierre Cassou-Noguès
doaj   +1 more source

Home - About - Disclaimer - Privacy