Results 71 to 80 of about 726,227 (317)

Development of a wind turbine simulator

open access: yesThe Journal of Engineering, 2019
As a renewable energy source, wind power has become a hot research topic, despite the lack of wind-environment simulation equipment in most laboratories.
Yuan Sun, Ji Zhang, Yanru Zhou
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Genetic programming and deductive-inductive learning: a multistrategy approach [PDF]

open access: yes, 1998
Proceedings of: 15th International Conference on Machine Learning, Madison (Wisconsin, USA), July 24-27, 1998.Genetic Programming (GP) is a machine learning technique that was not conceived to use domain knowledge for generating new candidate solutions ...
Borrajo, Daniel   +5 more
core  

Efficient Moving Object Segmentation in LiDAR Point Clouds Using Minimal Number of Sweeps

open access: yesIEEE Open Journal of Signal Processing
LiDAR point clouds are a rich source of information for autonomous vehicles and ADAS systems. However, they can be challenging to segment for moving objects as - among other things - finding correspondences between sparse point clouds of consecutive ...
Zoltan Rozsa   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Switched reluctance motor design for electric vehicles based on harmonics and back EMF analysis

open access: yesThe Journal of Engineering, 2019
Permanent magnet synchronous motors are widely accepted in automotive applications. The high torque density, high rotational speed with maximum efficiency in electric vehicle applications is technically challenging for motor design.
Abid Ali Shah Bukhari   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Statistical analysis of alignment characteristics for phrase-based machine translation [PDF]

open access: yes, 2010
In most statistical machine translation (SMT) systems, bilingual segments are extracted via word alignment. However, there lacks systematic study as to what alignment characteristics can benefit MT under specific experimental settings such as the ...
Petitrenaud, Simon   +7 more
core  

Torque optimisation of seven-phase BLDC machines in normal and degraded modes with constraints on current and voltage

open access: yesThe Journal of Engineering, 2019
This study proposes several easy-to-implement control strategies when seven-phase axial flux brushless DC machines with trapezoidal back electromotive forces operate in normal and faulty modes by taking into account constraints on voltage and current ...
Duc Tan Vu   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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