Results 71 to 80 of about 1,297,449 (284)

Theoretical Analysis and Optimum Design of High Speed Gas Film Thrust Bearings

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
This paper describes the theoretical and experimental investigations of static and dynamic characteristics of four types of high-speed gas film thrust bearings, such as stepped, pocketed, spiral and herring bone grooved bearings.
Hiromu HASHIMOTO, Masayuki OCHIAI
doaj   +1 more source

Experimental validation of FEA modelling of touch trigger probes [PDF]

, 2007
The authors have previously proposed the use of finite element method (FEM) for the modeling of coordinate measuring machine probes. Whilst the modeling results have been published previously, this paper presents the detailed experimental validation to ...
Jones, BE, Salleh, MR, Wei, P, Yang, QP
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Study of the Control Mechanism of a Half-Toroidal CVT during Load Transmission

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
In November 1999, the first vehicle with a traction drive CVT (continuously variable transmission) was manufactured and introduced to the market. The speed ratio changing mechanism of the half-toroidal CVT was theoretically analyzed by applying two ...
Shinji MIYATA, Darping LIU
doaj   +1 more source

A performance analysis of the PASLIB version 2.1X SEND and RECV routines on the finite element machine [PDF]

The Finite Element Machine is an experimental array processor designed to support research in parallel algorithms and architectures. This report presents a case study of communications using the SENDa and RECV system software routines on the Finite ...
Knott, J. D.
core   +1 more source

Influence of PWM on the proximity loss in permanent magnet brushless AC machines [PDF]

, 2008
The winding copper loss can be significantly increased due to skin and proximity eddy current effects. The skin and proximity losses due to fundamental frequency current has been investigated in literature, but the influence of PWM on the skin and ...
Bremner, J., Deodhar, R., Iwasaki, S., Liu, Y., Pride, A., Zhu, Z.Q.   +5 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Uninterrupted Transmission System for Realizing High Flexibility in Design of Angular Velocity Ratio

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
Geared transmissions are used in a variety of mechanical devices to realize a wide range of speeds or torques. However, the transmission of power and motion in a geared transmission is interrupted when the working gear pairs are changed to vary the ...
Jungchul KANG, Masaharu KOMORI
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Control Method for Output Speed during Velocity Ratio Change under High Rotational Speed Using an Uninterrupted Transmission System

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
Transmissions that can change their velocity ratio are used in various mechanical devices to achieve a wide range of torques or speeds. For machines with transmissions, such as transportation vehicles, it is required to keep the output speed or the ...
Jungchul KANG, Masaharu KOMORI, Shuai ZHANG, Koki SUGIYAMA   +3 more
doaj   +1 more source