Results 81 to 90 of about 189,037 (316)

Design of a five-axis ultra-precision micro-milling machine—UltraMill. Part 2: Integrated dynamic modelling, design optimisation and analysis

open access: yes, 2009
Using computer models to predict the dynamic performance of ultra-precision machine tools can help manufacturers to substantially reduce the lead time and cost of developing new machines. However, the use of electronic drives on such machines is becoming
Wardle, F, Cheng, K, Huo, D
core   +1 more source

The application of spectral kurtosis on Acoustic Emission and vibrations from a defective bearing [PDF]

open access: yes, 2011
The application of Acoustic Emission (AE) technology for machine health monitoring is gaining ground as power tool for health diagnostic of rolling element bearing.
Mba, David   +7 more
core   +1 more source

Effect of internal clearance on rolling element load of double row tapered roller bearings

open access: yesNihon Kikai Gakkai ronbunshu, 2016
An external load applied to a rolling bearing is distributed among the rolling elements. This rolling element load distribution is changed according to the way the external load is applied or the internal clearance of the bearing. And, it will affect the
Ken TAKAHASHI   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Thermal Error Modelling of a CNC Machine Tool Feed Drive System using FEA Method

open access: yes, 2016
Recirculating ball screw systems are commonly used in machine tools and are one of the major heat sources which cause considerable thermal drift in CNC machine tools.
Longstaff, Andrew P.   +5 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Machine structure simulation using FEA and optimised thermal parameters

open access: yes, 2015
Continuous usage of machine tools during manufacturing processes causes heat generation in the moving elements, resulting in distortion of the machine tool structure.
Longstaff, Andrew P.   +3 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Axial field permanent magnet DC motor with powder iron armature

open access: yes, 2007
The paper describes a double-gap axial field permanent magnet (PM) dc motor whose double-layer armature wave winding is constructed of copper strips.
Mohammad, Mohammad T.   +1 more
core   +1 more source

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