Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Design and Implementation of Machine Tool Life Inspection System Based on Sound Sensing. [PDF]
Liu TH +5 more
europepmc +1 more source
Evaluation and Comparison of a Large Machine Tool Structure with ISO Standard Alignment Tests
In order to satisfactorily machine precision components it is necessary for machine tools to be able to achieve extremely high levels of geometric accuracy.
Longstaff, Andrew P. +9 more
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Research on Intelligent Planning Method for Turning Machining Process Based on Knowledge Base
Against the backdrop of accelerating transformation in traditional mechanical manufacturing toward intelligent production models integrating mechanical, electronic, and information technologies, coupled with increasing demands for mass customization ...
Yante Li, Tingting Zhou
doaj +1 more source
Structural Design of a Special Machine Tool for Internal Cylindrical Ultrasonic-Assisted Electrochemical Grinding. [PDF]
Ma X +6 more
europepmc +1 more source
Rate-of-change analysis applied to machine tool monitoring and maintenance schedules
In high-value manufacturing, production equipment is often calibrated on a regular basis to ensure it remains within the required absolute tolerance. However, this go/no go approach means that data relating to the rate of change of the condition of the ...
Longstaff, Andrew P. +4 more
core
Development of a Novel MultiBody Mechatronic Model for Five-Axis CNC Machine Tool
The paper presents the development of a mechatronic hybrid model for Geiss five-axis CNC machine tool using MultiBody-System (MBS) approach. The motion control systems comprising electrical and mechanical elements are analyzed and modeled.
Pislaru, Crinela +2 more
core
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source

