Results 101 to 110 of about 471,211 (302)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Finite element analysis and structure optimization of a gantry-type high-precision machine tool. [PDF]

Sci Rep, 2023
Chan TC, Ullah A, Roy B, Chang SL.
europepmc   +1 more source

The Association catalogue; machine tools made in America; machines-utiles construites en Amérique; maquinas de construcción americana; amerikanische werk-zeug-maschinen ...

, 1921
Mode of access ...
National Machine Tool Builders' Association
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Ultrahigh electrostrain with exceptional temperature stability in BNT-based ceramics via synergistic regulation of critical phase and domain engineering

Journal of Advanced Ceramics
Bismuth sodium titanate-based (Bi0.5Na0.5TiO3, BNT) lead-free piezoelectric ceramics exhibit significant potential for precision actuation because of their large electrostrain.
Feng Zhang, Yaodong Yang, Jianting Li, Xiancheng Zhang, Junjie Li, Yimeng Tang, Shuo Qu, Yang Bai, Wei-Feng Rao   +8 more
doaj   +1 more source

Derivation of a cost model to aid management of CNC machine tool accuracy maintenance

, 2015
Manufacturing industries strive to produce improved component accuracy while not reducing machine tool availability or production throughput. The accuracy of CNC production machines is one of the critical factors in determining the quality of these ...
Longstaff, Andrew P., Fletcher, Simon, Shagluf, Abubaker, Longstaff, Andrew   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Design of a High-Speed Rotary Ultrasonic Machining Machine Tool for Machining Microstructure of Brittle Materials. [PDF]

Micromachines (Basel), 2023
Zhang S, Gong M, Lian H, Wu J, Zhu W, Ou Z.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dynamic Evaluation of the Degradation Process of Vibration Performance for Machine Tool Spindle Bearings. [PDF]

Sensors (Basel), 2023
Ye L, Zhang W, Cui Y, Deng S.
europepmc   +1 more source