Results 81 to 90 of about 471,211 (302)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Post heat treatment optimization of cold spray additive manufactured Inconel 718

Scientific Reports
The cold spray technique has recently emerged as an additive manufacturing method for producing free-standing parts, in addition to its use in repair and coating applications.
Aptullah Karakaş, Arash Ataee, Amit Rathi, Tevfik Ozan Fenercioğlu, Can Erdogan, Tuncay Yalçinkaya   +5 more
doaj   +1 more source

Aerodynamic Optimization of the Archimedes Spiral Wind Turbine Blade Based on the Kriging Surrogate Model and Differential Evolution

Energies
The Archimedes Spiral Wind Turbine (ASWT) is a novel horizontal axis wind turbine for urban low-wind-speed applications. To improve the wind energy capture efficiency of the ASWT, this study adopted a multivariable global optimization strategy.
Mengyao Li, Zhi Li, Shuhui Xu
doaj   +1 more source

Classification of drilling surface roughness on computer numerical control (CNC) machine tools based on Mobilenet_v3_small_improved [PDF]

Mechanical Sciences
Computer numerical control (CNC) machine tool drilling is a crucial process in the contemporary manufacturing sector, facilitating high-precision fabrication of complex components and thus enhancing production efficiency and product quality.
G. Chen, W. Peng, J. Tu, W. Wang, H. Zhao   +4 more
doaj   +1 more source

A Review on Real-Time Simulation of CNC Machine Tool Dynamics

, 2013
This paper is an endeavour to critically appraise the existing methods used for real-time simulation of machine tool dynamics with the emphasis on modelling and simulation of the dynamic behaviour of CNC machine tool feed drives and mechatronic systems ...
Pislaru, Crinela
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Effect of pulse frequency on microstructure and properties of laser additive manufactured Inconel 718

Journal of Materials Research and Technology
Laser additive manufacturing of Inconel 718 nickel-based superalloy (In718) typically results in coarse columnar grains, which adversely affect its mechanical properties.
Yuanjun Su, Jingjie Zhang, Guangchun Xiao, Hui Chen, Mingdong Yi, Zhaoqiang Chen, Hui Zhang, Chonghai Xu   +7 more
doaj   +1 more source

Defining and Computing Machine Tool Accuracy

, 2009
Understanding machine tool performance is important for specifying or comparing machines and for determining capability for production. Machine accuracy has generally been described by the linear positioning accuracy and repeatability of the axes.
Longstaff, Andrew P., Fletcher, Simon, Myers, Alan   +2 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Active Vibration Control for a CNC Milling Machine

, 2013
There is a requirement for improved three-dimensional surface characterisation and reduced tool wear when modern computer numerical control (CNC) machine tools are operating at high cutting velocities, spindle speeds and feed rates.
Longstaff, Andrew P., Myers, A., Lockwood, S., Longstaff, A., Haase, Frerk, Haase, F., Ford, Derek G., Ford, D. G., Myers, Alan, Lockwood, Stephen   +9 more
core   +1 more source