Results 81 to 90 of about 377,457 (261)

Technological robot-Machine tool collaboration for agile production. [PDF]

open access: yesFront Robot AI, 2022
Wabner M   +3 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Effect of dislocation slip on in-situ tensile fracture of vanadium alloys after helium/self-ion irradiation

open access: yesScience and Technology of Advanced Materials
Research on tensile fracture of vanadium alloys after irradiation would help evaluate their mechanical properties and service life in extreme environments of fusion reactors, thereby ensuring the safety and reliability of the materials.
Qianqian Zhang   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Ultrahigh electrostrain with exceptional temperature stability in BNT-based ceramics via synergistic regulation of critical phase and domain engineering

open access: yesJournal of Advanced Ceramics
Bismuth sodium titanate-based (Bi0.5Na0.5TiO3, BNT) lead-free piezoelectric ceramics exhibit significant potential for precision actuation because of their large electrostrain.
Feng Zhang   +8 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Performance improvement and friction reduction mechanism of Al2O3/Ti(C,N)/CaF2@Al2O3 self-lubricating ceramic tool for machining Cr15Ni60 alloy

open access: yesMaterials & Design
Nickel-based alloys commonly used in spacecraft and wear-resistant coatings have excellent hardness and corrosion resistance. However, their high strength presents great machining challenges.
Xixiang Xu   +7 more
doaj   +1 more source

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