Results 121 to 130 of about 8,730,293 (397)

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Closure to “Discussion of ‘A Three-Dimensional, Tool-Life Equation—Machining Economics’” (1959, ASME J. Eng. Ind., 81, p. 249) [PDF]

, 1959
Bertil N. Colding
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Machine Tool Tests and Alignments

Proceedings of the Institution of Mechanical Engineers, 1936
Limits and tolerances are the basis of all machine manufacture. Fourteen European countries adopted the system known as the ISA (International Federation of National Standards Associations) in December 1936; the system covers all grades of finish from the finest roller bearings to rough agricultural machines.
openaire   +4 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Research on Intelligent Planning Method for Turning Machining Process Based on Knowledge Base

Machines
Against the backdrop of accelerating transformation in traditional mechanical manufacturing toward intelligent production models integrating mechanical, electronic, and information technologies, coupled with increasing demands for mass customization ...
Yante Li, Tingting Zhou
doaj   +1 more source

A Study on Proposal of Flank Wear Criterion by Using a Built-in Current Sensor when Manufacturing the Mold Materials in a Smart Machine Tool

MATEC Web of Conferences, 2018
Recently, it has been increased with respect to the safe and reliable operations in industry of machine tools and intelligent of the machine tool has consistently been developing in term of an unmanned manufacturing.
Baek Seung-Yub, Jung Sung-Taek, Park Dae-Yu   +2 more
doaj   +1 more source

Machine Tools of Concrete, The Current Supplement, and more [PDF]

, 1918
Robert H. Moulton
openalex   +1 more source

The impact of family ownership on innovation: evidence from the German machine tool industry

Small Business Economics, 2016
There has been much debate concerning the innovative output of family-owned and non-family-owned companies. The purpose of this study was to show that the impact of family ownership differs depending on important governance conditions.
C. Decker, Christina Günther
semanticscholar   +1 more source