Results 51 to 60 of about 158,077 (267)

Measurement Parameters Optimized for Sequential Multilateration in Calibrating a Machine Tool with a DOE Method

open access: yesApplied Sciences, 2016
Improving volumetric error compensation is one of the machine tool user’s key objectives. Smart compensation is bound to calibration accuracy. Calibration quality depends largely on its setup factors.
Fabien Ezedine   +3 more
doaj   +1 more source

Modeling of CNC machine tools’ spatial geometric error based on two-dimensional angle error

open access: yesSN Applied Sciences, 2022
A modeling method of CNC machine tools’ spatial geometric error is proposed based on two-dimensional angle error in this paper. Different from traditional modeling method, this method takes into account the effect of additional angle errors because the ...
Xiuqin Zhang   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Effects of Cooling Systems on the Thermal Behaviour of Machine Tools and Thermal Error Models

open access: yesJournal of Machine Engineering, 2020
Today, cooling systems are increasingly applied to the structure of machine tools (MT). Unfortunately, to date there have been few efforts to precisely control these cooling systems, which inhibits the full utilisation of their potential to improve MT ...
Martin Mareš   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Geometric Error Analysis and Compensation of Rotary Axes of Five-axis Machine Tools

open access: yes工程科学与技术, 2020
The position independent geometric errors (PIGEs) of the rotating axes of five-axis machine tools caused by the assembly are the key factor to determine the accuracy of the machine. Quantization analysis of the influence of PIGEs on the accuracy of error
Shijie GUO, Dongsheng ZHANG
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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