Results 61 to 70 of about 6,815,752 (285)

Modeling of CNC machine tools’ spatial geometric error based on two-dimensional angle error

SN Applied Sciences, 2022
A modeling method of CNC machine tools’ spatial geometric error is proposed based on two-dimensional angle error in this paper. Different from traditional modeling method, this method takes into account the effect of additional angle errors because the ...
Xiuqin Zhang, Guohua Chen, Lin Zhang, Yongwen Hu, Jie Mao, Zhiyang Zhang   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Thermal error modelling of machine tools based on ANFIS with fuzzy c-means clustering using a thermal imaging camera [PDF]

, 2015
Thermal errors are often quoted as being the largest contributor to CNC machine tool errors, but they can be effectively reduced using error compensation.
Longstaff, Andrew P., Fletcher, Simon, Abdulshahed, Ali, Myers, Alan, Abdulshahed, Ali M., Longstaff, Andrew P.; id_orcid   +5 more
core   +1 more source

Modelling and simulation of CNC machine tool feed drives [PDF]

The paper presents a critical appraisal of existing methods for modelling and simulation of CNC machine tool feed drives. Their goal is the development of mathematical models which adequately replicate the dynamic behaviour of the actual machines.
Pislaru, Crinela, Moreno-Castaneda, V.Y., Ford, Derek G.   +2 more
core   +3 more sources

Measurement Parameters Optimized for Sequential Multilateration in Calibrating a Machine Tool with a DOE Method

Applied Sciences, 2016
Improving volumetric error compensation is one of the machine tool user’s key objectives. Smart compensation is bound to calibration accuracy. Calibration quality depends largely on its setup factors.
Fabien Ezedine, Jean-Marc Linares, Julien Chaves-Jacob, Jean-Michel Sprauel   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The application of ANFIS prediction models for thermal error compensation on CNC machine tools [PDF]

, 2015
Thermal errors can have significant effects on CNC machine tool accuracy. The errors come from thermal deformations of the machine elements caused by heat sources within the machine structure or from ambient temperature change.
Longstaff, Andrew P., Fletcher, Simon, Abdulshahed, Ali, Abdulshahed, Ali M., Longstaff, Andrew P.; id_orcid   +4 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Geometric Error Analysis and Compensation of Rotary Axes of Five-axis Machine Tools

工程科学与技术, 2020
The position independent geometric errors (PIGEs) of the rotating axes of five-axis machine tools caused by the assembly are the key factor to determine the accuracy of the machine. Quantization analysis of the influence of PIGEs on the accuracy of error
Shijie GUO, Dongsheng ZHANG
doaj