Results 61 to 70 of about 158,077 (267)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A dynamic machine tool circle test calibration method by R-test

MATEC Web of Conferences, 2018
With the continuous popularization of automation in the manufacturing industry and continuous improvement of production efficiency, new requirements have been put forward for the error detection of machine tool.
Qian dehou, Bi qingzhen
doaj   +1 more source

Root Cause Identification of Machining Error Based on Statistical Process Control and Fault Diagnosis of Machine Tools

Machines, 2017
The essence of the machining process is the interaction that occurs between machine tools and a workpiece under certain conditions of cutting parameters.
Hongrui Cao, Denghui Li, Yiting Yue
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Calculation of Tool Offset and Tool Radius Errors Based on On-Machine Measurement and Least Squares Method in Ultra-Precision Diamond Turning

Photonics
Metal mirrors will be widely used in the coming decades. Therefore, as one of the enabling technologies for metal optical freeform surface manufacturing, ultra-precision (UP) diamond turning error compensation has become a research hotspot.
Yao Peng, Han Ding, Dong Zhang, Miao Luo
doaj   +1 more source

Tooth surface deviation and mesh analysis of beveloid gears with parallel axis considering machine tool adjustment errors

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
The mathematical beveloid gear tooth surface model considering machine tool adjustment errors was derived. The definition and calculation process of tooth surface deviations along the tooth trace and profile directions for beveloid gear were proposed ...
Xingyu YANG, Chaosheng SONG, Caichao ZHU, Siyuan LIU   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Using the Segmented Iterative Learning Control Method to Generate Volumetric Error-Compensated Part Programs for Three-Axis CNC Milling Machine Tools

Journal of Manufacturing and Materials Processing, 2018
This study proposes using the iterative learning control method to adjust the volumetric error-compensated tool path, where the working volume motion accuracy of three-axis computerized numerical control (CNC) milling machine tools is increased by ...
Ying-Chen Lu, Syh-Shiuh Yeh
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source