Results 121 to 130 of about 8,584,927 (344)

Adjustment of uncertain model parameters to improve the prediction of the thermal behavior of machine tools

open access: yes, 2022
S.329-332Computer models, which simulate the thermo-elastic behavior of machine tools, are used for optimizing machine designs and more recently for controller-integrated online corrections.
Ihlenfeldt, Steffen   +4 more
core   +1 more source

Machine Learning Interatomic Potentials as Emerging Tools for Materials Science

open access: yesAdvances in Materials, 2019
Atomic‐scale modeling and understanding of materials have made remarkable progress, but they are still fundamentally limited by the large computational cost of explicit electronic‐structure methods such as density‐functional theory.
Volker L. Deringer   +2 more
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The significance of air pockets for modelling thermal errors of machine tools

open access: yes, 2013
It is well known, especially with the prevalence of compensation for geometric errors, that thermal error represents the most significant proportion of the total volumetric error of the machine tool. Thermal error in machine tools originates from changes
Longstaff, Andrew P.   +5 more
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Monitoring of the Noise Emitted by Machine Tools in Industrial Conditions

open access: yes, 2018
The paper presents an analysis of noise emitted by selected machine tools in a production hall (under industrial conditions). Noise monitoring is a fundamental task for maintaining workplaces which are safe and healthy.
J. Józwik   +3 more
semanticscholar   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Opening of Production Engineering Machine Tools Laboratory, 1961 -- 03

open access: yes, 1961
Opening of Production Engineering Machine Tools Laboratory, by O.E.
Swinburne Technical College
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy