Results 111 to 120 of about 8,584,927 (344)

Towards Machine Shop 4.0: A General Machine Model for CNC machine-tools through OPC-UA

, 2018
The Industry 4.0 philosophy promotes the digitalisation of manufacturing systems. This results in a transformation of the traditional manufacturing systems and creates new capabilities in the subjects of monitoring and control.
D. Mourtzis, Nikolaos T. Milas, Nikolaos Athinaios   +2 more
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

FEA-based design study for optimising non-rigid error detection on machine tools

, 2015
Non-rigid-body behaviour can have a considerable effect on the overall accuracy performance of machine tools. These errors originate from bending of the machine structure due to change in distribution of its own weight or from movement of the workpiece ...
Longstaff, Andrew P., Myers, A., Longstaff, A. P., Mian, Naeem S., Fletcher, Simon, Mian, N. S., Fletcher, S., Myers, Alan   +7 more
core  

Design of a five-axis ultra-precision micro-milling machine—UltraMill. Part 2: Integrated dynamic modelling, design optimisation and analysis

, 2009
Using computer models to predict the dynamic performance of ultra-precision machine tools can help manufacturers to substantially reduce the lead time and cost of developing new machines. However, the use of electronic drives on such machines is becoming
Wardle, F, Cheng, K, Huo, D
core   +1 more source

A direct comparison of the machining performance of a variax 5 axis parallel kinetic machining centre with conventional 3 and 5 axis machine tools

, 2003
The current trend within the Tool and Die manufacturing sector is to machine components directly from hardened material using high speed 5-axis machining.
Bäckström, Mikael,, Webb, Phil,, Rask, Kjell,, Gindy, Noel,, Larsson, Hans,, Geldart, Martin,   +5 more
core   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Thermal stiffness - a key accuracy indicator of the machine tools

, 2022
45484555Static and dynamic stiffness [N/m] determine the ability of solids to resist constant and variable loads. Both elastic characteristics of a machine tool effect their quality assessment. Thermal stiffness (comprising heat stiffness and temperature
Koriath, Hans-Joachim, Kuznetsov, Alexander P.   +1 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The need for open source software in machine learning

, 2007
Open source tools have recently reached a level of maturity which makes them suitable for building large-scale real-world systems. At the same time, the field of machine learning has developed a large body of powerful learning algorithms for diverse ...
Ratsch, Gunnar, Scholkopf, Bernhard, Vincent, P., LeCun, Y, Ong, C., Braun, M.L., Rasmussen, Carl Edward, Rasmussen, CE, Rätsch, G., Bengio, S., Müller, K.-R., Müller, KR, LeCunn, Yann, Muller, Klaus-Robert, Vincent , P., Pereira, Fernando, Vincent, Pascal, Bottou, Leon, Pereira, F, ,, Braun, ML, Ong, CS, Rasmussen, C.E., Smola, A, Sonnenburg, S., Holmes, G, Bengio, S, Weston, Jason, Williamson, RC, Sonnenburg, S, Williamson, Robert C., Bottou, L., Holmes, G., Ong, Cheng Soon, Pereira, F., Braun, M., Sonnenburg, Soren, Smola, Alexander, Williamson, R.C., Holmes , G., Schölkopf, B, Holmes, Geoffrey, Braun, Mikio L., Bengio, Samy, Schölkopf, B., Rasmussen, C., Williamson, R., Rätch, G, Weston, J, Smola, A., Ong, C.S., Müller, K., Bottou, L, Weston, J., Vincent, P, LeCun, Y.   +55 more
core  

High precision, fast and flexible calibration of robots and large multi-axis machine tools

, 2022
Paper 12041, 6 S.The precise and detailed metrological axis system calibration of robots and large machine tools still requires the utilization of several different measurement instruments and causes an uneconomic machine downtime about several days ...
Brecher, Christian, Flore, Jakob, Haag, Sebastian, Wenzel, Christian   +3 more
core