Results 51 to 60 of about 709,475 (267)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Post-editing for the kazakh language using opennmt

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2022
The modern world and our immediate future depend on applied intelligent systems, as new technologies develop every day. One of the tasks of intelligent systems is machine (automated) translation from one natural language to another.
D. R. Rakhimova   +1 more
doaj   +1 more source

A retrospective view on the promise on machine translation for Bahasa Melayu-English [PDF]

open access: yes, 2010
Research and development activities for machine translation systems from English language to others are more progressive than vice versa. It has been more than 30 years since the machine translation was introduced and yet a Malay language or Bahasa ...
Jamaludin, Zulikha   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Equivalence Levels of Literary Corpus Translation Using a Freeware Analysis Toolkit

open access: yesBuletin Al-Turas, 2021
Machine translation has the potential to make huge contributions to translation industries, but it seems, for now, that machine translation equivalence has led to a crucial point for literary translation by using machine translation because of the ...
Frans Sayogie, Moh. Supardi
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

A Comparative Study of English-Persian Translation of Neural Google Translation [PDF]

open access: yesIranian Journal of Applied Language Studies, 2017
Many studies abroad have focused on neural machine translation and almost all concluded that this method was much closer to humanistic translation than machine translation.
Mina Zand Rahimi   +2 more
doaj   +1 more source

Findings of the 2019 Conference on Machine Translation (WMT19) [PDF]

open access: yes, 2019
This paper presents the results of the premier shared task organized alongside the Conference on Machine Translation (WMT) 2019. Participants were asked to build machine translation systems for any of 18 language pairs, to be evaluated on a test set of ...
Barrault, Loïc   +5 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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