Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Comparative Study of English-Persian Translation of Neural Google Translation [PDF]
Many studies abroad have focused on neural machine translation and almost all concluded that this method was much closer to humanistic translation than machine translation.
Mina Zand Rahimi +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Development and validation of machine translation literacy scale for translation education
The rise of machine translation demands a fundamental shift in both translators’ roles and educational approaches. However, translation education research and practice have struggled to keep pace with the latest developments.
Junho Lee, Sowon Ahn, Yeong-Houn Yi
doaj +1 more source
INTEGRATING MACHINE TRANSLATION AND SPEECH SYNTHESIS COMPONENT FOR ENGLISH TO DRAVIDIAN LANGUAGE SPEECH TO SPEECH TRANSLATION SYSTEM [PDF]
This paper provides an interface between the machine translation and speech synthesis system for converting English speech to Tamil text in English to Tamil speech to speech translation system.
J. SANGEETHA, S. JOTHILAKSHMI
doaj
MACHINE TRANSLATION, MACHINE TRANSLATION SYSTEMS AND THEIR SPECIFICATIONS
The article is devoted to the study of machine translation, machine translation systems and their specificity. The relevance of the work is determined by fast and strong changes of auto-translators and sharply increasing, qualitatively changing needs.
Hlib Danylov +2 more
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Dual-channel deep graph convolutional neural networks
The dual-channel graph convolutional neural networks based on hybrid features jointly model the different features of networks, so that the features can learn each other and improve the performance of various subsequent machine learning tasks.
Zhonglin Ye +15 more
doaj +1 more source

