Results 81 to 90 of about 158,952 (313)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Kernel regression based machine translation

, 2007
We present a novel machine translation framework based on kernel regression techniques. In our model, the translation task is viewed as a string-to-string mapping, for which a regression type learning is employed with both the source and the target ...
Zhuoran Wang, Wang, Z, Shawe-Taylor, John, Szedmak, S, John Shawe-taylor, Sandor Szedmak, Szedmak, Sandor, Shawe-Taylor, J, Wang, Zhuoran   +8 more
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

TMX markup: a challenge when adapting SMT to the localisation environment [PDF]

, 2010
Translation memory (TM) plays an important role in localisation workflows and is used as an efficient and fundamental tool to carry out translation. In recent years, statistical machine translation (SMT) techniques have been rapidly developed, and the ...
Andy Way, Way, Andy, Jinhua Du, Johann Roturier, Roturier, Johann, Du, Jinhua   +5 more
core  

Syntactic phrase-based statistical machine translation [PDF]

, 2006
Phrase-based statistical machine translation (PBSMT) systems represent the dominant approach in MT today. However, unlike systems in other paradigms, it has proven difficult to date to incorporate syntactic knowledge in order to improve translation ...
Hearne, M., Hearne, Mary, Andy Way, Sima'an, Khalil, Mary Hearne, Hassan, Hany, Sima\u27an, Khalil, Hany Hassan, Way, A., Hassan, H., Khalil Sima'an, Sima'an, K., Way, Andy   +12 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Sublanguages in machine translation [PDF]

Proceedings of the fifth conference on European chapter of the Association for Computational Linguistics -, 1991
There have been various attempts at using the sublanguage notion for disambiguation and the selection of target langauge equivalents in machine translation. In this paper a theoretical concept and its implementation in a real MT application are presented. Above this, means of linguistic engineering like weighting mechanisms are proposed.
openaire   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A SYSTEMATIC READING IN STATISTICAL TRANSLATION: FROM THE STATISTICAL MACHINE TRANSLATION TO THE NEURAL TRANSLATION MODELS.

Journal of ICT, 2017
Achieving high accuracy in automatic translation tasks has been one of the challenging goals for researchers in the area of machine translation since decades.
Zakaria El Maazouzi, Badr Eddine El Mohajir, Mohammed Al Achhab   +2 more
doaj   +3 more sources