Results 41 to 50 of about 4,784,113 (302)

Average roughness of machined surface with different cutting parameters.

open access: yes, 2018
Average roughness of machined surface with different cutting parameters.
Pingxiang Cao (5746559)   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Rake Angle Effect on a Machined Surface in Orthogonal Cutting of Graphite/Polymer Composites

open access: yesAdvances in Materials Science and Engineering, 2018
Graphite and its composites have been widely used in various industrial fields. It has been generally accepted that, for positive rake angles, there is a significant increase in tension stress at the cutting zone during the machining of brittle materials,
Dayong Yang   +3 more
doaj   +1 more source

Tool Wear and Machined Surface Roughness during Wood Flour/Polyethylene Composite Peripheral Up-milling using Cemented Tungsten Carbide Tools

open access: yesBioResources, 2014
The effect of sharpness angle on tool wear and the effect of tool wear on machined surface roughness were investigated in wood flour/polyethylene composite (WFPEC) peripheral up-milling using cemented tungsten carbide (TC) tools.
Xiaolei Guo   +4 more
doaj   +1 more source

Laser Micro Machining Of Material Surfaces [PDF]

open access: yesSPIE Proceedings, 1989
For high precision fabrication of fine structures and for making fine surface textures - a predefined finishing roughness on surfaces - several laser processing techniques are developed at TNO. The laser micro milling technique is applicable to make blind holes, grooves and other programmed shapes. It is a self—adjusting technique applicable e.g.
Krieken, A.H. van   +2 more
openaire   +2 more sources

Residual Stresses in Machining of AISI 52100 Steel under Dry and Cryogenic Conditions: A Brief Summary [PDF]

open access: yes, 2014
17th Conference on Material Forming (ESAFORM) - FinlandResidual stress is one of the most important surface integrity parameter that can significantly affect the service performance of a mechanical component, such as: contact fatigue, corrosion ...
OUTEIRO, José   +5 more
core  

Fractal dimensions and surface roughness of the machined surfaces.

open access: yes, 2019
Fractal dimensions and surface roughness of the machined surfaces.
Lei Yu (70258)   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Residual Stresses Induced by Dry and Cryogenic Cooling during Machining of AZ31B Magnesium Alloy [PDF]

open access: yes, 2014
The major challenge of the Mg alloys has been their unsatisfactory corrosion resistance, which can be enhanced by improving the surface integrity. Cryogenic machining, where liquid nitrogen was used during machining, has been reported to improve the ...
MARQUES, Maria José   +6 more
core  

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