Results 51 to 60 of about 4,784,113 (302)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Analysis of Tool Wear and Roughness of Graphite Surfaces Machined Using MCD and NCD-Coated Ball Endmills

open access: yesMicromachines, 2022
The high-purity G5 graphite material is widely used for glass moulding and provides high hardness and brittleness because it is sintered to fine particles unlike other graphite materials.
Hyeonhwa Lee   +3 more
doaj   +1 more source

Surface Texture’s Role in Assessing Surface Integrity of Machined Parts

open access: yes, 2010
Surface texture, as one of the typical surface integrity characteristics, plays a vital part in efficiently and systematically evaluating the surface integrity and relevant mechanical properties of machined parts.
Rui Ting Tong   +3 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Characterization of Polyamide (PA-6) Processed at Different Parameters on the Sliding Automatic Machine

open access: yesInternational Journal of Automotive Science and Technology
In this study, the surface roughness, hardness, and microstructure of polyamide (PA6), a widely used material in the manufacturing industry, were compared with machined PA6 under different machining parameters on a sliding automatic lathe.
İhsan Küçükrendeci   +3 more
doaj   +1 more source

Characterization of electric discharge machining of titanium alloy utilizing MEIOT technique for orthopedic implants

open access: yesMaterials Research Express, 2021
In this research work, medical grade titanium alloy Ti4Al6V was electric discharge machined with an objective of attaining mirror finish for orthopedic implants.
Manoj Prabhakar B S   +2 more
doaj   +1 more source

Study on the Effect of Milling Surface Plastic Deformation on Fatigue Performance of 20Cr and TC17 Specimens

open access: yesMetals, 2022
In addition to the micro-topography of machined surfaces, plastic deformation is an important factor affecting the machined surface integrity and the fatigue performance of specimens. For 20Cr and TC17 materials, the effect law of milling surface plastic
Xun Li   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Monte Carlo Simulation of Morphology Evolution of Machined Surface

open access: yes, 2011
Monte Carlo (MC) method is adopted to simulate the morphology evolution of machined surface. One specimen is first scratched in MD simulation, and then the machined surface is used in MC simulation.
Jia Xuan Chen   +2 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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