Results 81 to 90 of about 4,784,113 (302)

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

The effect of cutting parameters on surface integrity in milling TI6AL4V

open access: yesSouth African Journal of Industrial Engineering, 2016
The objective of machining performance is to reduce operational costs and to increase the production rate while maintaining or improving the required surface integrity of the machined component.
Oosthuizen, Tiaan   +3 more
doaj   +1 more source

Machine learning in nephrology: scratching the surface

open access: yesChinese Medical Journal, 2020
Abstract Machine learning shows enormous potential in facilitating decision-making regarding kidney diseases. With the development of data preservation and processing, as well as the advancement of machine learning algorithms, machine learning is expected to make remarkable breakthroughs in nephrology.
Qi Li   +8 more
openaire   +3 more sources

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

OPTICAL SURFACE ROUGHNESS MEASUREMENT OF MACHINED SURFACES [PDF]

open access: yes, 1990
An optical method is described that makes measurement of surface roughness of machined parts in a wide roughness range possible. The apparatus based on a diode laser can be mounted on CNC machining centers as diagnostic tool for checking tool wear ...
PÉCZELI, I., BERKES, O., RICHTER, P.
core   +1 more source

TRIBOLOGY AND TOPOGRAPHY OF HARD MACHINED SURFACES

open access: yesCutting & Tools in Technological System, 2021
In machining automotive industrial parts by hard machining procedures, the topographic characteristics of high accuracy surfaces have high importance. In this paper 2D and 3D surface roughness features of gear bores machined by hard turning and grinding are demonstrated.
openaire   +2 more sources

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

High speed machined surface roughness measurement

open access: yes, 2010
Surface roughness monitoring techniques using non-contact methods based on computer vision technology are becoming popular and cost effective. An evolvable hardware configuration using reconfigurable Xilinx Virtex FPGA xcv1000 architecture with ...
S Gowri   +7 more
core   +1 more source

Characterisation of the relationship between surface texture and surface integrity of superalloy components machined by grinding [PDF]

open access: yes, 2013
The surface texture of a machined component is influenced largely by the processing parameters used during machining and hence, there is a relationship between both the formation of the surface texture and surface integrity of the machined component.
Qin, Yi   +3 more
core   +5 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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