Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
A Machine Learning Framework for Solving High-Dimensional Mean Field\n Game and Mean Field Control Problems [PDF]
Lars Ruthotto +4 more
openalex +1 more source
Machine Learning Assisted Prediction of Cathode Materials for Zn‐Ion Batteries [PDF]
Linming Zhou +5 more
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Predictions of the mechanical properties of unidirectional fibre composites by supervised machine learning [PDF]
M.V. Pathan +6 more
openalex +1 more source
Combination Cancer Treatment: Using Engineered DNAzyme Molecular Machines for Dynamic Inter‐ and Intracellular Regulation [PDF]
Ruo‐Can Qian +6 more
openalex +1 more source
Sustainable machining - correlation of the optimization by minimum energy, minimum manufacturing time and cost of production [PDF]
The machining process leads the indices of productivity and employability in a world level and has an enormous influence at social and economics standards, however it requires machinery that consume high levels of energy, chemical fluids and has great ...
Pascoal, Filipa, Silveira, José
core
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source

