Results 131 to 140 of about 119,208 (317)

Machine consciousness

open access: yesScholarpedia, 2005
The work from several laboratories on the modeling of consciousness is reviewed. This ranges, on one hand, from purely functional models where behavior is important and leads to an attribution of consciousness to, on the other hand, material work closely derived from the information about the anatomy of the brain. At the functional end of the spectrum,
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Behaviour laws comparison for titanium alloys machining: Application to Ti5553 [PDF]

open access: yes, 2009
The aircraft industry uses materials more and more efficient. This trend affects the majority of parts such as structure parts. Titanium alloy (Ti-5AL-5Mo-5V-3CR) is now used for the production of landing gear. There are many goals in this paper.
Wagner, Vincent   +3 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Experimental study of thin part vibration modes in machining [PDF]

open access: yes, 2008
The machining of thin walls generally generates milling chatter, that damage surface roughness and manufacturing tools. Stability lobes which include natural frequencies are successful in case of tool chatter.
Arnaud, Lionel   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

A comparative study on trajectory tracking control methods for automated vehicles

open access: yesScientific Reports
Trajectory tracking control, as the core component of the autopilot system, is essential for achieving high-performance autopilot functionality. Therefore, to design a trajectory-tracking controller that is stable, reliable, accurate, fast, and robust ...
Dequan Zeng   +8 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Modelling and experimental study of laser-assisted milling of fibre reinforced SiC/Ti-6Al-4V metal matrix composite

open access: yesMaterials & Design
Metal matrix composites (MMCs) offer unique advantageous mechanical properties by strengthening a ductile metal matrix with a ceramic reinforcement (e.g., Ti6Al-4 V/SiCf).
Omkar Mypati   +5 more
doaj   +1 more source

Identification of the heat input during dry or MQL machining [PDF]

open access: yes, 2012
Machining with minimum quantity lubrication (MQL) has been the focus of many scientific investigations since the last 20 years. Nevertheless an acceptable method of predicting the thermal influences on the workpiece quality has still not been developed ...
KOPPKA, Frank   +3 more
core  

Home - About - Disclaimer - Privacy