Results 121 to 130 of about 119,208 (317)
CoRR, 2020 Molecular robotics is challenging, so it seems best to keep it simple. We consider an abstract molecular robotics model based on simple folding instructions that execute asynchronously. Turning Machines are a simple 1D to 2D folding model, also easily generalisable to 2D to 3D folding. A Turning Machine starts out as a line of connected monomers in the
Irina Kostitsyna, Cai Wood, Damien Woods
openaire +4 more sources
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Advanced Techniques for Monitoring, Simulation and Optimization of Machining Processes
, 2011 In today’s manufacturing industry, pressure for productivity, higher quality and cost saving is heavier than ever. Surviving in today’s highly competitive world is not an easy task, contemporary technology updates and heavy investments are needed in ...
Keshari, Anupam
core
Electronic Notes in Theoretical Computer Science, 2016 AbstractWe present a general method – the Machine – to analyse and characterise in finitary terms natural transformations between well-known functors in the category Pol of Polish spaces. The method relies on a detailed analysis of the structure of Pol and a small set of categorical conditions on the domain and codomain functors.
Fredrik Dahlqvist +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Cryogenic cooling-based sustainable machining
, 2020 Machinability is the most important indicator to measure the performance of any machining operation. Cutting force, surface roughness, tool wear, dimensional accuracy, and cutting temperature, etc. are the most important machinability indicators. Various
Bayraktar, Şenol, Senol Bayraktar
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Effect of electro discharge machining (EDM) on the AISI316L SS white layer microstructure and corrosion resistance [PDF]
, 2013 The localised corrosion resistance of austenitic stainless steels is strongly influenced by the quality of finished surface. EDM machining induces substantial changes by the high thermal gradients generated by electric sparks.
SIDHOM, Habib +4 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source