Results 71 to 80 of about 3,545,542 (409)

Fundamental Investigation of the Application Behavior and Stabilization Potential of Milling Tools with Structured Flank Faces on the Minor Cutting Edges

Journal of Manufacturing and Materials Processing
In milling processes in which material removal is performed periodically from solid material, dynamic effects are generally considered to be responsible for instabilities and subsequent productivity limits.
Raphael Isaak Elias Schönecker, Jonas Baumann, Rafael Garcia Carballo, Dirk Biermann   +3 more
doaj   +1 more source

Simulation of Residual Stresses in Surface and Subsurface Layer after Machining

Communications, 2016
This article deals with non-destructive detection method of residual stress as analytical tool of expected distribution of residual stress in surface and sub-surface layers.
Andrej Czan, Michal Sajgalik, Jozef Holubjak, Marianna Piesova, Tatiana Czanova   +4 more
doaj   +1 more source

Conduction-Based Thermally Assisted Micromilling Process for Cutting Difficult-to-Machine Materials

Journal of Manufacturing and Materials Processing, 2020
The increasing demand for complex and wear-resistant forming tools made of difficult-to-machine materials requires efficient manufacturing processes. In terms of high-strength materials; highly suitable processes such as micromilling are limited in their
Timo Platt, Alexander Meijer, Dirk Biermann   +2 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Kinematic modelling of a 3-axis NC machine tool in linear and circular interpolation

, 2010
Machining time is a major performance criterion when it comes to high-speed machining. CAM software can help in estimating that time for a given strategy.
B Sencer, I Korkut, K Erkorkmaz, L Tapie, M Monreal, MC Tsai, N Tounsi, RZ Xu, S Lavernhe, S Nam, V Flores, V Pateloup, Walter Rubio, X Liu, Xavier Pessoles, Yann Landon   +15 more
core   +3 more sources

Experimental study on lapping ceramic balls with variable-radius groove plate

Advances in Mechanical Engineering, 2021
The method of lapping precision ball with variable-radius groove is developed in recent years. An experimental study on lapping ceramic balls with variable-radius groove was carried out.
Fenfen Zhou, Weifeng Yao, Julong Yuan, Binghai Lyu, Tianchen Zhao, Ping Zhao   +5 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Design of ultraprecision machine tools with application to manufacturing of miniature and micro components [PDF]

, 2005
Currently the underlying necessities for predictability, producibility and productivity remain big issues in ultraprecision machining of miniature/microproducts.
Chen, Dave Webb, EI-Fatatry, Frank Wardle, Gabler, Huang, Ikawa, Kai Cheng, Liu, Luo, McKeown, Nakazawa, Schellekens, Shinno, Slocum, Stephenson, Webster, Weck, Weck, Wybranski, Xichun Luo   +20 more
core   +1 more source

Application of an Ultrashort-pulsed Laser for Generation of Super-hydrophobic Surfaces

Current Directions in Biomedical Engineering, 2021
Hydrophobic surfaces have gained a vast attention in different fields of biomedical applications over the last few years. Laser treatment has been shown as a promising technology for the generation of functional, inter alia, superhydrophobic surfaces. In
Zahedi Ali, Jauch Christian, Azarhoushang Bahman   +2 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source