Results 121 to 130 of about 87,256 (241)

Modelling of material cutting with a material microstructure-level (MML) model [PDF]

open access: yes, 2013
In this research work a material microstructure-level cutting model (MML cutting model) is presented. The crystal plasticity theory is adopted for modeling the cutting of the titanium alloy Ti–6Al–4V in orthogonal case.
Mabrouki, Tarek   +2 more
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Auxiliary propulsion thruster performance with ion machined accelerator grids [PDF]

open access: yes
A substantial improvement in the performance of an 8-centimeter-diameter auxiliary propulsion thruster was achieved by reducing the diameter of the accelerator grid apertures.
Hudson, W. R.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

TECHNOLOGICAL ASSURANCE OF MECHANICAL PROCESSING OF COMPLEX SHAPED PARTS BASED ON MACHINING CENTERS WITH NUMERICAL CONTROL

open access: yesJournal of Engineering Science (Chişinău)
To achieve high precision in the machining of complex-shaped parts, the correct combination of technologies with the machining center is necessary, especially if it has only 3 axes, to obtain the best results.
BÎCIOC, Mihail
doaj   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams   +14 more
wiley   +1 more source

Design and Machining of a Spherical Shell Rotor for a Magnetically Levitated Momentum Ball

open access: yesAerospace
Ball-shell rotors with non-standard shapes, non-uniform conductive coatings, and eccentric masses machined by conventional processes constrain the improvement of levitation and torque accuracy of magnetically levitated momentum balls.
Limei Ma   +6 more
doaj   +1 more source

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