Results 101 to 110 of about 5,151,847 (295)

Performance Evaluation of Independent Quality Labs Inc. Supertune on Haas Vertical Machining Center

open access: yes, 2009
The goal of this project is to evaluate improvements in accuracy, curve-following ability, and damping resulting from an Independent Quality Labs, Inc supertune on a Haas vertical machining center.
Stefaniak, Christopher
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A Comprehensive Evaluation Method of Machining Center Components’ Importance Based on Combined Variable Weight

open access: yesMathematics
The fault transitivity of machining center components causes their fault propagation indexes to demonstrate dynamic time variability, which affects their importance. The method proposed in this study overcomes the biases of existing methods of evaluating
Lan Luan, Guixiang Shen, Yingzhi Zhang
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Study on the Application of QFD Technology in the Whole Conceptual Design of Special-Shaped Stone Machining Center

open access: yes, 2011
The Quality Function Deployment (QFD) model and the optimal decision-making model is applied to the design of special-shaped stone Machining Center. Through the establishment of Design of house of quality of Machining Center, it can convert the users ...
Yan Liu, Ke Zhang, Nan Xiao, Yu Hou Wu
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Abrasive machining with MQSL. [PDF]

open access: yes, 2011
Grinding and polishing of engineered components are critical aspects of the precision manufacturing of high performance, quality assured products. Elevated process temperatures, however, are a common and for the most part undesirable feature of the ...
Morris, Tom
core   +2 more sources

长锥距弧齿锥齿轮的加工参数设计与加工试验

open access: yesJixie chuandong, 2012
For its cone distance dimension is very large,long-cone-distance spiral bevel gear is milled on the large scale special purpose machine tool generally,and the process is difficult to realize.Using pre-control technique of the tooth contact bearings,the ...
张华, 徐增军, 朱云振, 雷宝珍
doaj  

Machining centers for nanoindustry [PDF]

open access: yesNanoindustry Russia, 2015
D. Korostelev, D. Yaminsky, I. Yaminsky
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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