Results 101 to 110 of about 88,069 (311)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Approximation Model Development and Dynamic Characteristic Analysis Based on Spindle Position of Machining Center. [PDF]
Materials (Basel), 2022 Kim JW +5 more
europepmc +1 more source
The new robotics—towards human‐centered machines [PDF]
HFSP Journal, 2007 Research in robotics has moved away from its primary focus on industrial applications. The New Robotics is a vision that has been developed in past years by our own university and many other national and international research institutions and addresses how increasingly more human-like robots can live among us and take over tasks where our current ...
openaire +2 more sources
Analysis of cutting parameters in point machining of parts with complex shape [PDF]
, 2018 This paper presents developed SW module in the postprocessor, which is designed to backward analysis of CAM milling toolpath. The module is designed to analyze multi-axis finishing machining of complex shape parts with milling cutters with a circular ...
Rybín J. +3 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Dynamic analysis of lathe bed of woodworking CNC machining center based on the modeling of joint surface. [PDF]
PLoS One, 2022 Sun YK, Hua J, Li YN, Chen GW, Liu MH.
europepmc +1 more source
Growing Ohio's Green Energy Economy [PDF]
, 2009 Provides an overview of the state's solar, wind, biomass, and geothermal energy and fuel cell industries and assesses their economic contribution and potential for growth.
Amy Gomberg, Wren Kruse
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Chatter Monitoring of Machining Center Using Head Stock Structural Vibration Analyzed with a 1D Convolutional Neural Network. [PDF]
Sensors (Basel), 2022 Jeong K +4 more
europepmc +1 more source
CNC electrical discharge machining centers [PDF]
, 1991 Computer numerical control (CNC) electrical discharge machining (EDM) centers were investigated to evaluate the application and cost effectiveness of establishing this capability at Allied-Signal Inc., Kansas City Division (KCD). In line with this investigation, metal samples were designed, prepared, and machined on an existing 15-year-old EDM machine ...
openaire +2 more sources